Efflux twj yog cov membrane proteins uas koom nrog hauv kev xa tawm cov khoom tsis zoo los ntawm cov kab mob hauv lub cell mus rau sab nraud. Lawv muaj nyob rau hauv txhua hom kab mob, thiab efflux twj genes tuaj yeem pom nyob rau hauv cov kab mob chromosomes lossis cov caj ces ntawm tes, xws li plasmids.
Cov kab mob twg siv cov twj efflux?
Efflux twj tso kua mis tau tshaj tawm tias yog ib qho ntawm cov txheej txheem ua haujlwm rau cov tshuaj tiv thaiv kab mob hauv cov txheej txheem biofilm. Cov pov thawj ntawm lub luag hauj lwm ntawm efflux twj tso kua mis nyob rau hauv biofilm kuj tau pom nyob rau hauv ntau yam kab mob xws li Pseudomonas aeruginosa, Escherichia coli thiab Candida albicans.
Lub hom phiaj ntawm efflux twj tso kua mis yog dab tsi?
Efflux twj tso kua mis yuav tsum tau colonization thiab tshaj tawm thaum lub sij hawm tus tswv tsev kis kab mob los ntawm ntau cov kab mob pathogenic thiab tuaj yeem pab cov kab mob extrude innate host defence. Qhov no yog qhov tseeb tshwj xeeb hauv Neisseria, uas siv RND efflux twj rau extrude host antimicrobial fatty acids thiab antimicrobial peptides.
efflux twj tso kua mis hauv biology yog dab tsi?
Efflux twj yog thauj cov proteins koom nrog hauv kev tshem tawm cov tshuaj lom hauv substrates(nrog rau txhua chav kawm ntawm cov tshuaj tua kab mob cuam tshuam) los ntawm cov hlwb mus rau sab nraud. Cov proteins no muaj nyob rau hauv ob qho tib si Gram-positive thiab -negative kab mob nrog rau cov kab mob eukaryotic.
tib neeg puas muaj cov twj tso kua mis?
Tseeb, nws tau qhia tias tusVibrio cholerae efflux twj tso kua mis VexB yog lub thawj efflux systemlub luag haujlwm rau cov kua tsib ntsev hauv cov kab mob no [149]. Txij li thaum cov kua tsib ntsev muaj nyob rau hauv tib neeg lub plab, qhov kev ua ntawm lub twj tso kua mis efflux no yog qhov yuav tsum tau ua ua ntej rau tus kab mob V. cholerae.
