Lub alkylation ntawm acetylide ions yog ib qho tseem ceeb hauv cov organic synthesis vim nws yog cov tshuaj tiv thaiv uas tsim cov carbon-carbon tshiab; yog li ntawd, nws tuaj yeem siv tau thaum tus kws tshuaj organic tab tom sim tsim cov molecule nyuaj los ntawm ntau cov khoom pib yooj yim.
Acetylide tsim yog dab tsi?
Ib acetylide anion yog ib qho anion tsim los ntawm kev tshem tawm cov proton los ntawm qhov kawg carbon ntawm lub davhlau ya nyob twg alkyne: Cov kua qaub yog cov npe ntawm cov khoom sib xyaw ua ke kom nce lossis txo acidity.
Acetylides siv rau dab tsi?
Acetylides ntawm hom RC2M tau dav siv hauv alkynylations hauv cov tshuaj lom neeg cov tshuaj lom neeg. Lawv yog nucleophiles uas ntxiv rau ntau yam ntawm electrophilic thiab unsaturated substrates. Daim ntawv thov classic yog Favorskii cov tshuaj tiv thaiv.
Anion acetylide tsim li cas?
Yog li ntawd, acetylide anions tuaj yeem tsim tau yooj yim by deprotonation siv lub hauv paus muaj zog txaus . Amide anion (NH2-), nyob rau hauv daim ntawv ntawm NaNH2 yog feem ntau siv rau kev tsim ntawm acetylide anions.
Puas yog acetylide zoo nucleophile?
Acetylide anions yog muaj zog hauv paus thiab muaj zog nucleophiles. Yog li ntawd, lawv muaj peev xwm tshem tawm halides thiab lwm pab pawg tawm hauv kev hloov pauv. Cov khoom yog hloov alkyne.
