2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Tus neeg ua si tseem ceeb hauv cov txheej txheem catalytic hauv cov serine proteases yog catalytic triad catalytic triad A catalytic triad yog ib pawg ntawm peb pawg amino acidsuas tuaj yeem pom hauv cov nquag qhov chaw ntawm qee cov enzymes. Catalytic triads feem ntau pom muaj nyob rau hauv hydrolase thiab transferase enzymes (xws li proteases, amidases, esterases, acylases, lipases thiab β-lactamases). https://en.wikipedia.org › wiki › Catalytic_triad
Catalytic triad - Wikipedia
. … Cov serine muaj ib pawg -OH uas muaj peev xwm ua tau raws li ib tug nucleophile, tawm tsam cov carbonyl carbon ntawm scissile peptide daim ntawv cog lus ntawm substrate.
Yuav ua li cas serine protease inhibitors ua haujlwm?
Serine protease inhibitors, lossis serpins, suav nrog tsev neeg cov proteins uas antagonize cov haujlwm ntawm serine proteases. … Hauv qhov txheej txheem no, tus serpin nthuav tawm lub substrate-mimicking peptide sib lawv liag-lub reactive center voj-rau nws lub hom phiaj serine protease.
Lub luag haujlwm dab tsi hauv cov tshuaj tiv thaiv serine protease yog ua los ntawm cov nqi xa hluav taws xob?
Lub luag haujlwm ntawm Asp102 hauv catalytic relay system ntawm serine proteases yog kawm theoretically los ntawm xam cov hluav taws xob dawb ntawm ib leeg proton-hloov cov tshuaj tiv thaiv los ntawm Asn102 mutant trypsin thiab cov concerted ob proton-hloov cov tshuaj tiv thaiv (hu ua tus nqi-relay mechanism) ntawm cov tsiaj qus-hom trypsin.
Qhov twg hauv qab no yog piv txwv ntawm serine protease?
Chymotrypsin: >Siv ua piv txwv ntawm serine protease vim nws cov qauv thiab cov txheej txheem tau nkag siab zoo.
yog vim li cas thiaj hu ua serine proteases?
Lawv hu ua serine proteases rau ob qho laj thawj:
- Lawv hydrolyze proteins.
- Lawv muaj qhov tseem ceeb Ser residue ntawm qhov chaw nquag uas yog qhov tseem ceeb rau catalysis. Qhov tseeb no Ser yog ntau reactive dua lwm yam serines nyob rau hauv cov protein.
Pom zoo:
Hauv schultze mechanism ntawm placental sib cais?
Nyob rau hauv txoj kev Schultze, kev sib cais pib nyob rau hauv qhov chawntawm cov placenta (fetal nto), thiab qhov no yuav nqis los ua ntej, nrog rau qhov seem tom qab. … Kev tswj cov ntshav tom qab yug me nyuam tshwm sim los ntawm kev cog lus thiab thim rov qab ntawm interlacing myometrial fibers nyob ib puag ncig leej niam cov hlab ntsha ntawm lub txaj placental.
Hauv elliptical trammels mechanism?
A trammel ntawm Archimedes yog lub tshuab uas tsim cov duab ntawm lub voj voog. Nws muaj ob lub shuttles uas raug kaw("trammeled") rau perpendicular channels lossis rails thiab tus pas nrig uas txuas rau lub shuttles los ntawm pivots ntawm qhov chaw ruaj khov raws tus pas nrig.
Nyob rau hauv psychodynamic txoj kev xav dab tsi yog kev tiv thaiv mechanism?
Cov txheej txheem tiv thaiv yog tus cwj pwm tib neeg siv cais lawv tus kheej ntawm cov xwm txheej tsis zoo, kev ua, lossis kev xav. Cov tswv yim kev puas siab puas ntsws no yuav pab tau tib neeg kom nyob deb ntawm lawv tus kheej thiab kev hem lossis kev xav tsis zoo, xws li kev ua txhaum lossis kev txaj muag.
Leej twg detering nyob rau hauv tag nrho cov nyob ntsiag to nyob rau sab hnub poob pem hauv ntej?
Detering yog tus neeg ua liaj ua teb los ntawm Txhua Tus Neeg Tsis Txaus Siabntawm Sab Hnub Poob los ntawm Erich Maria Remarque. Nws muaj siab mos siab muag, tshwj xeeb tshaj yog thaum nws los txog rau nees. Nws muaj kev kub ntxhov loj heev thaum nws hnov cov nees quaj thiab txawm sim tua lawv kom kawg lawv txoj kev txom nyem.
Dab tsi yog serine protease inhibitor?
Serine protease inhibitors, lossis serpins, suav nrog ib tsev neeg ntawm cov proteins uas tiv thaiv kev ua haujlwm ntawm serine proteases. Cov proteins no inhibit protease kev ua los ntawm kev txuag cov txheej txheem uas cuam tshuam nrog kev hloov pauv loj (raws li kev tshuaj xyuas hauv Miranda thiab Lomas, 2006;
