Noradrenaline yog degraded los ntawm Monoamine oxidase A, uas muaj FAD ua cofactor. Monoamine oxidase nyob rau hauv sab mitochondrial membrane ntsibcytoplasmic site.
Noradrenaline metabolised li cas?
Metabolism ntawm NorepinephrineNorepinephrine yog metabolized los ntawm
cov enzymes monoamine oxidase thiab catechol-O-methyltransferase rau 3-methoxy-4-hydroxymandelic acid thiab 3-methoxy-4-hydroxyphenylglycol (MHPG).
Qhov twg yog norepinephrine metabolized?
Cov metabolism ntawm norepinephrine hauv lub hlwb feem ntau zoo ib yam li hauv lub peripheral sympathetic system. Hauv ob qho tib si, tyrosine hloov mus rau norepinephrine intraneuronally, ua raws tib txoj kev enzymatic.
Norepinephrine puas tawg tau li cas?
Norepinephrine kev ua tau zoo raug txiav los ntawm inactivationlos ntawm cov enzymes catechol-O-methyltransferase (COMT) los yog monoamine oxidase (MAO), los ntawm reuptake mus rau hauv cov hlab ntsha xaus, los yog diffusion los ntawm binding sites.
Puas yog norepinephrine metabolized los ntawm COMT?
Norepinephrine yog metabolized ntawm monoamine oxidases (MAO-A thiab MAO-B) tom qab rov ua dua rau hauv lub cell, lossis los ntawm catechol-O-methyltransferase (COMT) tom qab diffusion mus rau hauv lub cell. kev ncig. Pharmacological cov neeg ua haujlwm uas cuam tshuam rau txoj hauv kev no yog siv rau kev kho mob ntshav siab, kev nyuaj siab, thiab kev txav mus los.
