2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
DNase Kuv qhov chaw puas siab puas ntsws pom qhov twg thiab lawv qhia dab tsi txog qhov xwm txheej ntawm chromatin? Cov chaw no muaj nyob ntawm exon-intron junctions thiab qhia qhov chaw ntawm mRNA cleavage thaum lub sij hawm splicing. Cov chaw no raug random pom thoob plaws hauv genome thiab nws ua rau DNA yooj yim rau degradation.
DNase kuv qhov chaw hypersensitive yog dab tsi thiab nws cuam tshuam li cas chromatin?
Nyob hauv noob caj noob ces, DNase I hypersensitive sites (DHSs) yog cov cheeb tsam ntawm chromatin uas nkag siab rau kev sib cais los ntawm DNase I enzyme. Hauv cov cheeb tsam tshwj xeeb ntawm genome, chromatin tau poob nws cov qauv condensed, nthuav tawm DNA thiab ua rau nws nkag mus tau.
DNase hypersensitive site qhia dab tsi?
Cov ntsiab lus cis-kev tswj hwm yog qhov ua rau muaj kev cuam tshuam los ntawm endonuclease DNase I. Motifs nyob rau hauv DNase I hypersensitive sites qhia muaj peev xwm hloov pauv qhov ua haujlwm nyob thiab, thaum ua ke nrog DNase I cleavage cov ntaub ntawv, tuaj yeem siv los tsim cov kev tswj xyuas ib ntus.
DNase kev ntsuas ntshav siab yog dab tsi?
Rau ntau tshaj li ob xyoo lawm, DNase I hypersensitivity assay (DHA) tau instrumental rau nrhiav pom cov cai tswj hwm(11). Txoj kev no qhia cov chaw sib cais hauv cov genome uas qhov sib haum ntawm chromatin ua rau nws cov DNA hypersensitive rau cleavage los ntawm endonuclease DNase I (12).
Nuclease hypersensitive site hauv chromatin yog dab tsi?
Ibchromatin, nucleosome-free regions hu ua nuclease hypersensitive sites ntseeg tau tias sawv cev rau "qhib qhov rais" uas tso cai rau kev nkag mus tau zoo ntawm cov neeg nyob hauv cis-acting DNA ib ntus rau cov yam ntxwv hloov pauv(saib Refs.
Pom zoo:
Kev tsis ncaj ncees nyob qhov twg yog qhov hem rau kev ncaj ncees nyob txhua qhov chaw?
Martin Luther King tau hais tias: “Kev tsis ncaj ncees nyob txhua qhov chaw yog kev hem thawj rau kev ncaj ncees nyob txhua qhov chaw. Peb raug ntes nyob rau hauv ib tug inescapable network ntawm kev sib nrig sib pab, khi nyob rau hauv ib lub tsoos tsho ntawm txoj hmoo.
Cov kws kho kev puas siab puas ntsws ua haujlwm nyob qhov twg?
Cov kws kho kev puas siab puas ntsws feem ntau ua haujlwm hauv tsev kawm ntawv(piv txwv li theem pib, nruab nrab, qib qis, thiab siab), cov koom haum pabcuam kev sib raug zoo, tsev kho mob, chaw kho mob, chaw kho mob, tsev laus, kev coj ua ntiag tug, kev tshawb fawb lab, thiab kev lag luam.
Nyob hauv tib neeg lub ntsws ntsws thaum twg?
Thaum koj ua pa, lossis nqus pa, koj diaphragm cog lus thiab txav mus rau hauv qab. Qhov no ua rau qhov chaw nyob hauv koj lub hauv siab kab noj hniav hauv siab kab noj hniav [2] Cov kab noj hniav thoracic muaj kabmob thiab cov ntaub so ntswguas ua haujlwm hauv lub ntsws (ntsws, bronchi, trachea, pleura), hlab plawv (lub plawv, pericardium).
Cov kws paub txog kev puas siab puas ntsws ua haujlwm nyob qhov twg?
Qee tus kws kho kev puas siab puas ntsws ua haujlwm ib leeg, nrog cov neeg mob thiab cov neeg siv khoom tuaj rau ntawm tus kws kho mob hlwb. Lwm tus tau koom nrog pab pawg saib xyuas kev noj qab haus huv thiab feem ntau ua haujlwm hauv tsev kho mob, tsev kawm kho mob, chaw kho mob sab nraud, tsev laus, chaw kho mob, chaw kho mob, thiab chaw kho mob hauv zej zog thiab kev puas siab puas ntsws.
Lub tsev kho mob puas siab puas ntsws hloov chaw nyob qhov twg?
Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tsev Kho Mob kis thoob plaws lub tsev kawm ntawv ntawm 172.8 acres hauv Agra nyob rau pem hauv ntej ntawm Bilochpura Railway Station ze Sikendra. Puas yog Agra tsev kho mob puas siab puas ntsws hloov?
