Raws li kev nplua basophilic stippling hauv thalassemia, basophilic stippling feem ntau yog ntxhib hauv cov tshuaj lom neeg txhuas ua los ntawm nag lossis daus ntawm RNA theem nrab rau pyrimidine-5′-nucleotidase inhibition. Coarse basophilic stippling kuj tau tshaj tawm hauv pyrimidine-5'-nucleotidase deficiency thiab arsenic lom.
Dab tsi ua rau basophilic stippling ntawm RBC?
Lub xub ntiag ntawm basophilic stippling yog ntaus nqi rau aggregates ntawm ribosomes los yog fragments ntawm ribosomal RNA precipitated thoob plaws hauv lub cytoplasm ntawm circulating erythrocytes. Qhov kev tshawb pom no cuam tshuam nrog cov kab mob hematological uas tau txais thiab muaj txiaj ntsig zoo cuam tshuam rau erythropoiesis thiab erythrocyte maturation.
Cov xwm txheej twg muaj basophilic stippling?
Basophilic stippling yog pom nyob rau hauv lead lom, impaired Hb synthesis, cawv, thiab megaloblastic anemias (Daim duab 61.6A).
Puas yog basophilic stippling ib txwm?
Basophilic stippling yog qhov qhia txog disturbed erythropoiesis. Nws kuj tuaj yeem pom hauv qee tus neeg ib txwm muaj.
Yuav ua li cas cov tshuaj lom lead ua rau Microcytic Hypochromic anemia thiab qaug zog?
Cov kab mob ntshav qab zib feem ntau pom yog microcytic, hypochromic anemia, tab sis qhov no yuav yog vim muaj lwm yam ua rau xws li tsis muaj hlau. Lub mechanism ntawm lub nplhaib sideroblasts muaj feem xyuam rau cov tsub zuj zuj ntawm hlau-laden mitochondria nyob rau hauv cov ntshav liab precursors vim rau inhibition ntawm ferrochelatase los ntawmcoj.
