Nyob rau xyoo 1980s American neurologist Stanley B. Prusiner Prusiner Prusiner loj hlob hauv Cincinnati, Ohio, thiab tau kawm hauv University of Pennsylvania (A. B., 1964; M. D., 1968). Tom qab siv plaub xyoos hauv kev tshawb fawb txog biochemical, nws tau los ua (1972) ib tus neeg nyob hauv neurology ntawm University of California, San Francisco, Tsev Kawm Ntawv Tshuaj. Tsab ntawv xov xwm no tshwm sim thawj zaug https://www.britannica.com › biography › Stanley-B-Prusiner
Stanley B. Prusiner | American biochemist thiab neurologist
thiab cov npoj yaig txheeb xyuas "cov kab mob sib kis kab mob," lub npe uas luv luv rau "prion" (hais tias "pree-on").
Leej twg pom cov kab mob sib kis?
Lub sijhawm xyoo 1960, ob tus kws tshawb fawb hauv London, hluav taws xob biologist Tikvah Alper thiab biophysicist John Stanley Griffith, tau tsim qhov kev xav tias qhov kis tau tus kab mob spongiform encephalopathies yog tshwm sim los ntawm tus kab mob sib kis. tsuas yog cov proteins xwb.
leej twg thawj zaug pom prions?
Koj Tus Huab Tais, Koj Cov Nom Tswv, Cov Poj Niam thiab Cov Poj Niam, Xyoo Nobel nqi zog hauv Physiology lossis Tshuaj tau txais txiaj ntsig rau Stanley B. Prusinerrau nws qhov kev tshawb pom ntawm prions - ib qho tshiab biological txoj cai ntawm kev kis kab mob.
Prusiner nrhiav tau prions li cas?
Nyob rau xyoo 1982, tom qab kaum xyoo ntawm kev tshawb fawb, nws thiab nws pab neeg tau tsim ib qho kev npaj los ntawm lub hlwb hamster uas muaj cov kab mob sib kis tsuas yog ib qho protein xwb. Prion proteins(PrP), Prusiner pom, yog "ob tus neeg sawv cev," uas muaj nyob hauv ob qho tib si ib txwm ua raws (PrPc) thiab kab mob ua rau muaj kev sib haum xeeb (PrPSc).
Thaum twg Prusiner pom prions?
Nyob hauv 1982 Stanley Prusiner tau cais tus neeg mob uas xav tias muaj kab mob, cov protein uas nws hu ua prion.
