Cov cheeb tsam uas tsis tau txhais lus (UTRs) hauv mRNA ua si lub luag haujlwm tseem ceeb ntawm kev tswj hwm kev ruaj ntseg, kev ua haujlwm, thiab thaj chaw ntawm mRNA. 3'-UTRs ntawm mRNA kuj tseem ua cov qauv rau miRNA khi uas tswj kev hloov pauv thiab / lossis kev ua haujlwm ntawm mRNA.
Lub hom phiaj ntawm thaj chaw tsis tau txhais ntawm mRNA yog dab tsi?
Nyob rau hauv cov eukaryotes siab dua, cov cheeb tsam uas tsis tau txhais lus (UTRs) ntawm cov ntawv sau tseg yog ib qho ntawm tus tswj hwm tseem ceeb ntawm cov noob qhia (cuam tshuam rau mRNA kev ruaj ntseg thiab kev txhais lus zoo). Parasitic protozoan genome kev tshawb fawb tau coj mus rau tus cwj pwm (hauv silico, hauv vitro thiab hauv vivo) ntawm ntau tus ntawm lawv cov noob.
Lub luag haujlwm ntawm tsis txhais yog dab tsi?
UTRs ntawm NDV sib txawv ntawm qhov ntev thiab ua ntu zus. … UTRs hauv cov kab mob tau pom tias ua lub luag haujlwm hauv txoj cai ntawm kis kab mob thiab kev txhais lus. Hauv tus kab mob khaub thuas A, UTRs muaj cov cim qhia lub luag haujlwm rau RNA replication, transcription, polyadenylation, thiab ntim ntawm RNA ntu (19).
Lub hom phiaj ntawm thaj chaw tsis tau txhais ntawm mRNA Chav Kawm 12 yog dab tsi?
Ib qho mRNA kuj muaj qee qhov sib txuas ntxiv uas tsis tau txhais thiab raug xa mus ua thaj chaw tsis tau txhais (UTR). UTRs muaj nyob rau ntawm ob qho tib si 5'-kawg (ua ntej pib codon) thiab ntawm 3'-kawg (tom qab nres codon) uas yog xav tau rau cov txheej txheem txhais lus zoo.
Lub luag haujlwm dab tsi ua cov cheeb tsam tsis tau txhais ntawm mRNA ntu ua si hauv cov proteinsynthesis?
Cov cheeb tsam uas tsis tau txhais lus muab kev ruaj ntseg rau mRNA thiab tseem nce kev txhais lus ua haujlwm tau zoo.
