Phosphoglucomutase (EC 5.4. 2.2) yog ib qho enzyme uas hloov cov phosphate pawg ntawm α-D-glucose monomer los ntawm 1 mus rau 6 txoj hauj lwm nyob rau pem hauv ntej los yog 6 mus rau 1 txoj hauj lwm nyob rau hauv txoj kev rov qab.. Ntau precisely, nws pab txhawb kev sib cuam tshuam ntawm qabzib 1-phosphate thiab qabzib 6-phosphate.
Lub luag haujlwm ntawm hexokinase yog dab tsi?
Hexokinase yog thawj enzyme ntawm glycolysis, catalyzing phosphorylation ntawm qabzib los ntawm ATP rau qabzib-6-P. Nws yog ib qho ntawm cov enzymes txwv glycolysis. Nws cov dej num poob sai sai raws li lub hnub nyoog qub qub.
Cov tshuaj tiv thaiv twg yog catalysed los ntawm phosphoglucomutase?
Phosphoglucomutase (PGM) catalyzes kev sib hloov ntawm qabzib-1-phosphate (G-l-P) thiab qabzib-6-phosphate (G-6-P), uas sawv cev rau ceg taw tes nyob rau hauv carbohydrate metabolism.
Txoj kev twg siv phosphoglucomutase?
Cov enzyme koom nrog txoj kev glycogenolysis. Thaum ib tug 1-phosphate qabzib molecule raug tso tawm los ntawm glycogen los ntawm glycogen phosphorylase, phosphoglucomutase catalyses lub interconversion ntawm no kuj siv tsis tau metabolic intermediate rau 6-phosphate qabzib.
YPuas yog phosphoglucomutase hauv glycolysis?
Phosphoglucomutase-1 yog ib qho enzyme tseem ceeb hauv glycolysisthiab glycogenesis los ntawm kev hloov pauv hauv bidirectional ntawm phosphate los ntawm txoj hauj lwm 1 txog 6 ntawm cov piam thaj. Glucose-1-P thiab UDP-glucose yog zetxuas rau galactose metabolism. Kev ua haujlwm PGM1 ib txwm yog qhov tseem ceeb rau kev ua haujlwm zoo glycolysis thaum yoo mov.
