Lipogenesis yog txhawb nqa los ntawm kev noj zaub mov carbohydrate siab, thaum nws yog inhibited los ntawm polyunsaturated fatty acids thiab yoo mov. Cov teebmeem no yog ib feem kho los ntawm cov tshuaj hormones, uas inhibit (kev loj hlob hormone, leptin) lossis txhawb nqa (insulin) lipogenesis.
YYuav pib lipogenesis dab tsi?
Lipogenesis yog cov txheej txheem cuam tshuam nrog kev sib txuas ntawm fatty acids lossis triglycerides, uas yog tswj hwm thiab tswj los ntawm ntau yam hauv lub cev. Cov txheej txheem yog txhawb nqa los ntawm noj zaub mov ntau hauv carbohydrates thiab ntau cov tshuaj hormones hauv lub cev, xws li insulin, kho cov txheej txheem.
Yuav ua li cas enzyme koom nrog hauv kev tswj hwm lipogenesis?
Enzymes lub hauv paus rau cov txheej txheem ntawm lipogenesis yog cov uas catalyze fatty acid biosynthesis: acetyl-coenzyme A carboxylase (ACC); fatty acid synthase; thiab ATP-citrate lyase, uas ua lub luag haujlwm hauv kev hloov pauv ntawm acetyl-coenzyme A (acetyl-CoA) los ntawm mitochondrion mus rau cytosol, qhov twg fatty acid synthesis tshwm sim (…
Cov tshuaj hormone twg inhibit lipolysis thiab txhawb lipogenesis?
Glucagon kuj ua raws li cov tshuaj lipolytic uas txhawb kev tawg ntawm triglycerides los ntawm cov lipid droplets [63]. Insulin tawm dag zog tawm tsam, txhawb adipogenesis thiab inhibiting lipolysis [64].
Vim li cas insulin txhawb lipogenesis?
Insulin txhawb nqa lipogenesis los ntawm kev ua kom cov piam thaj nkag, tswj cov qib ntawm glycerol-3-P thiab lipoproteinlipase (LPL).
