Kanamycin A belongs rau tsev neeg ntawm aminoglycoside tshuaj tua kab mob uas lub hom phiaj cellular RNA txhawm rau tiv thaiv kab mob thiab kis kab mob.
Kanamycin puas tsom cov kab mob gram-zoo lossis tsis zoo?
Kanamycin A zoo ib yam li streptomycin thiab neomycines, thiab nws muaj qhov dav dav ntawm cov tshuaj tiv thaiv kab mob. Nws yog nquag nrog kev hwm rau feem ntau Gram-positive thiab Gram-negative microorganisms (staphylococci, colon bacillus, klebisella, Fridlender's bacillus, proteus, shigella, salmonella).
kanamycin cuam tshuam rau cov kab mob hom phiaj li cas?
Kanamycin yog tshuaj tua kab mob aminoglycoside. Aminoglycosides ua haujlwm los ntawm kev khi rau cov kab mob 30S ribosomal subunit,
ua rau kev nyeem tsis raug ntawm t-RNA, ua rau cov kab mob tsis tuaj yeem tsim cov proteins tseem ceeb rau nws txoj kev loj hlob.
Kanamycin inhibit cell loj hlob li cas?
Kanamycin cuam tshuam nrog 30S ribosomal subunit uas ua rau muaj ntau qhov kev txhais lus tsis raug thiab tiv thaiv kev hloov pauv thaum lub sij hawm tsim cov protein [27, 28], whereas tetracyclines khi rau 16S ib feem ntawm 30S ribosomal subunit thiab tiv thaiv cov amino-acyl tRNA mus txuas rau ntawm A-site ntawm mRNA-ribosome complex, …
Yuav ua li cas yog lub mechanism ntawm kev txiav txim ntawm kanamycin?
Kanamycin yog cov tshuaj tua kab mob aminoglycoside siv los kho cov kab mob sib txawv. Kanamycin ua haujlwm los ntawm khi rau cov kab mob 30S ribosomal subunit, ua rau kev nyeem tsis raug ntawm mRNA thiab tawm hauv cov kab mob. Cov kab mob tsis tuaj yeem tsim cov proteins tseem ceeb rau nws txoj kev loj hlob.
