Neutrophils tuaj yeem nthuav tawm antigens rau antigen-specific nco CD4+T cells tab sis MDCs thiab monocytes muaj peev xwm tshaj plaws.
Dab tsi yog cov antigen nthuav tawm cov hlwb?
Antigen-presenting cells (APCs) yog ib pawg neeg tsis muaj zog tiv thaiv kab mob uas kho cov kab mob hauv lub cev los ntawm kev ua thiab nthuav tawm cov tshuaj tiv thaiv rau kev lees paublos ntawm qee cov lymphocytes xws li T hlwb. Classical APCs suav nrog cov hlwb dendritic, macrophages, Langerhans hlwb thiab B hlwb.
Pob neutrophils puas muaj MHC kuv?
Txawm li cas los xij, neutrophils qhia MHC-I (1, 2, 3) thiab tau raug pom los nthuav qhia MHC-I- txwv peptides (7).
Macrophages ua li cas muaj cov tshuaj tiv thaiv?
Ib APC, xws li macrophage, engulfs thiab zom cov kab mob txawv teb chaws. Ib qho tshuaj tiv thaiv kab mob los ntawm cov kab mob tau nthuav tawm ntawm lub xov tooj ntawm tes nrog rau MHC II molecule Lymphocytes ntawm kev hloov lub cev tiv thaiv kab mob cuam tshuam nrog antigen-embeddedMHC II molecules kom paub tab rau hauv lub cev tiv thaiv kab mob.
YDo neutrophils nthuav qhia HLA-DR?
Neutrophils yog cov hlwb ntawm lub cev tiv thaiv kab mob. Stimulated los ntawm interferon-γ (IFN-γ) los qhia HLA-DR, neutrophils tau txais cov khoom siv ntawm tes ua haujlwm rau superantigen- mediated T cell ua kom.
