Senile plaques yog polymorphous beta-amyloid protein deposits pom nyob rau hauv lub hlwb hauv Alzheimer kab mob thiab kev laus ib txwm. Qhov no beta-amyloid protein yog muab los ntawm ib tug loj precursor molecule ntawm uas neurons yog tus tseem ceeb tsim nyob rau hauv lub hlwb.
pom amyloid plaques nyob qhov twg?
Amyloid plaques yog cov sib sau ua ke ntawm cov proteins tsis zoo uas tsim nyob rau hauv qhov chaw nruab nrab ntawm cov paj hlwb. Cov proteins uas txawv txav no tau xav tias ua lub luag haujlwm tseem ceeb hauv Alzheimer's disease. Cov plaques amyloid thawj zaug tsim nyob rau hauv thaj chaw ntawm lub hlwb cuam tshuam nrog kev nco thiab lwm yam kev paub txog kev ua haujlwm.
plaque hauv hlwb tuaj qhov twg?
Plaques daim ntawv thaum cov khoom protein hu ua beta-amyloid (BAY-tuh AM-uh-loyd) sib sau ua ke. Beta-amyloid los ntawm cov protein ntau pom nyob rau hauv fatty membrane nyob ib ncig ntawm cov hlab ntsha. Beta-amyloid yog tshuaj "nqa" thiab maj mam tsim mus rau hauv cov quav hniav.
Qhov twg ua rau neurofibrillary tangles thiab senile plaques tshwm sim?
Neurofibrillary tangles yog insoluble twisted fibers pom hauv lub hlwb hlwb. Cov tangles no feem ntau yog cov protein hu ua tau, uas yog ib feem ntawm cov qauv hu ua microtubule. Lub microtubule pab thauj cov as-ham thiab lwm yam tseem ceeb ntawm ib feem ntawm cov paj hlwb mus rau lwm qhov.
Cov plaques thiab tangles nyob qhov twg?
Alzheimer's feem ntau yogtxuam nrog ob hom kab mob thoob plaws cerebral cortex: amyloid plaques, uas pom ntawm cov neurons, thiab neurofibrillary tangles, uas pom hauv lawv.
