Angiogenesis txhais tau tias kev loj hlob ntawm cov hlab ntsha tshiab. Yog li cov tshuaj tiv thaiv angiogenic yog kho mob uas txwv cov qog los ntawm kev loj hlob ntawm lawv cov hlab ntsha. Yog tias cov tshuaj muaj peev xwm tiv thaiv tau tus kab mob qog noj ntshav los ntawm cov hlab ntsha loj tuaj, nws yuav ua rau kev loj hlob ntawm cov qog nqaij hlav qeeb lossis qee zaum qis dua.
Lub hom phiaj ntawm kev kho mob angiogenesis yog dab tsi?
Qee zaum hu ua antiangiogenic therapy, qhov kev kho no tuaj yeem tiv thaiv kev loj hlob ntawm qog nqaij hlav los ntawm kev thaiv cov hlab ntsha tshiab los ntawm kev tsim. Angiogenesis inhibitor therapy tuaj yeem khov kho cov qog thiab tiv thaiv kom tsis txhob loj hlob ntxiv. Los yog nws yuav txo qhov loj ntawm cov qog.
Yuav ua li cas tiv thaiv kev kho mob angiogenic ua haujlwm?
Cov kws tshawb fawb tau tsim cov tshuaj hu ua angiogenesis inhibitors, lossis kev kho mob los tiv thaiv angiogenic, txhawm rau cuam tshuam txoj kev loj hlob . Cov tshuaj no tshawb nrhiav thiab khi lawv tus kheej rau VEGF molecules, uas txwv tsis pub lawv los ntawm kev ua kom cov receptors ntawm cov hlwb endothelial hauv cov hlab ntsha. Bevacizumab (Avastin®) ua haujlwm li no.
YYuav ua li cas piv txwv ntawm angiogenesis?
Piv txwv li, cov qog nqaij hlav tso tawm angiogenic loj hlob yam proteins uas txhawb cov hlab ntsha kom loj hlob mus rau hauv cov qog, muab cov pa oxygen thiab cov as-ham. Ib qho tseem ceeb ntawm txoj kev kho antiangiogenic cuam tshuam nrog cov txheej txheem ntawm cov hlab ntsha loj hlob kom cia cov qog ntawm nws cov ntshav.
Yuav ua li cas piv txwv ntawm kev kho mob angiogenesis?
Kev kho mob angiogenesis tau tshuaj xyuas dav dav rau kev kho mob ntau yam ntawm tib neeg. Lwm cov txheej txheem, xws li kev kho qhov txhab thiab kho lub cev thiab rov tsim dua tshiab, kuj yog nyob ntawm cov ntshav txaus. Cov tswv yim rau kev kho mob angiogenesis suav nrog noob xa, xa protein thiab xa xov ntawm tes.
