2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Humoral hypercalcemia ntawm malignancy (HHM) yog tshwm sim los ntawm oversecretion ntawm parathyroid hormone-related peptide (PTHrP) los ntawm cov qog malignant. Txawm hais tias ib qho qog tuaj yeem ua rau HHM, uas tshwm sim los ntawm intrahepatic cholangiocarcinoma (ICC) lossis mob qog noj ntshav (GC) tsis tshua muaj.
Puas yog hypercalcemia yog malignancy?
Hypercalcemia ntawm malignancy yog ib qho pom pom feem ntau hauv cov neeg mob uas mob qog noj ntshav siab. Hypercalcemia ntawm malignancy feem ntau tshwm sim nrog cov qib calcium uas nce siab thiab cov neeg mob yog li ntawd feem ntau mob hnyav.
Ntau npaum li cas hypercalcemia ntawm malignancy?
Hypercalcemia feem ntau tshwm sim hauv cov neeg mob qog noj ntshav, tshwm sim hauv kwv yees li 20 txog 30 feem pua ntawm cov neeg mob [1]. Nws yog feem ntau ua rau hypercalcemia nyob rau hauv tus neeg mob qhov chaw.
kev humoral hypercalcemia ntawm malignancy kho li cas?
Kev txhawb nqa ib txwm rau hypercalcemia suav nrog tshem cov calcium kom tsawg los ntawm txhua qhov chaw(xws li cov tshuaj calcium hauv cov hlab ntsha lossis qhov ncauj), ua kom cov dej tsis muaj qhov ncauj, txwv tsis pub noj tshuaj thiab tshuaj ntxiv uas ua rau hypercalcemia. (thiazide diuretics, lithium, vitamin D, calcium carbonate therapy), nce…
Puas pob txha malignancy ua rau hypercalcemia?
Hypercalcemia tshwm sim thaum cov pob txha tso calcium ntau dhaulossis lub raum tsis tuaj yeem tshem tawm cov calcium txaus. Qee cov qog nqaij hlav tuaj yeemua rau nws, tshwj xeeb tshaj yog cov theem ntawm cov qog nqaij hlav hauv qab no: ntau yam myeloma.
Pom zoo:
Hypercalcemia yog dab tsi?
High hypercalcemia - Cov neeg mob nrog tag nrho albumin kho calcium >14 mg/dL (3.5 mmol/L) xav tau kev kho mob hnyav dua. Raws li tau piav qhia saum toj no, cov neeg mob uas muaj qhov hnyav nce hauv cov ntshav calcium mus rau ntau theem nruab nrab uas muaj kev hloov pauv hauv cov sensorium (xws li, lethargy, stupor) kuj xav tau kev kho mob hnyav.
Yuav ua li cas hypercalcemia ua rau polyuria?
Txog 20% ntawm cov neeg mob nrog hypercalcemia tsim polyuria. Cov txheej txheem postulated yog downregulation ntawm aquaporin-2 dej raws, thiab calcium deposition nyob rau hauv lub medulla nrog ob tug tubulointerstitial raug mob, ua rau impaired tiam ntawm interstitial osmotic gradient.
Dab tsi yog kev xav ntawm autonomists dab tsi yog qhov kev xav ntawm kev zoo nkauj ntawm kev coj ncaj ncees?
Kev lig kev cai, muaj ob txoj haujlwm tawm tsam kev xav txog kev coj ua raws li kev cai lij choj ntawm kev ntsuas kev ncaj ncees ntawm kev kos duab: 'kev coj ncaj ncees kev ncaj ncees Ethics lossis kev coj ncaj ncees yog ib ceg ntawm kev xav uas "
Puas calcium ntxiv ua rau hypercalcemia?
Zoo: Kev siv ntau ntawm calcium thiab vitamin D supplementation tuaj yeem pom tau tias yog hypercalcemia thiab ua rau lub raum ua haujlwm tsis zoo hauv cov tib neeg raug mob. Kev paub ntawm cov kws saib xyuas kev noj qab haus huv tuaj yeem ua rau muaj kev kawm zoo rau cov neeg mob txog cov kev pheej hmoo kev noj qab haus huv no.
Puas yog tsib theem ntawm kev loj hlob ntawm kev puas siab puas ntsws?
Ntawm tsib theem kev puas siab puas ntsws, uas yog qhov ncauj, qhov quav, phallic, latent, thiab qhov chaw mos, thaj chaw erogenous cuam tshuam nrog txhua theem ua haujlwm zoo siab. … Yog hais tias cov theem kev puas siab puas ntsws ua tiav tiav, tus cwj pwm noj qab haus huv yog qhov tshwm sim.
