Feem ntau cov histamine nyob rau hauv lub cev yog tsim nyob rau hauv granules nyob rau hauv mast cells thiab hauv cov qe ntshav dawb (leukocytes) hu ua basophils. Mast hlwb tshwj xeeb tshaj yog ntau ntawm cov chaw uas muaj peev xwm raug mob - qhov ntswg, qhov ncauj, thiab ko taw, sab hauv lub cev, thiab cov hlab ntsha.
Histamine secreting cells pom dab tsi?
Mast cells yog cov hlwb loj nrog cov cytoplasm ntom ntom uas pom muaj nyob hauv cov ntaub so ntswg sib txuas. Lawv cov granules muaj histamine uas yog vasodilator, heparin uas yog ib qho tshuaj tiv thaiv coagulant thiab serotonin uas ua tus neeg nruab nrab ntawm kev mob thiab kev tsis haum tshuaj.
Cov hlwb ntawm cov ntaub so ntswg uas zais cov tshuaj histamine?
Mast Cells pom nyob ze rau cov hlab ntsha me hauv cov ntaub so ntswg xoob. Lawv muaj loj secretory granules ntawm heparin proteoglycan - tsis muaj zog anticoagulant. Lawv kuj muaj cov tshuaj histamine, uas txhawb cov tshuaj tiv thaiv inflammatory thaum secreted.
Histamine nyob qhov twg hauv lub cev?
Ntau cov histamine hauv lub cev yog tsim los ntawm granules hauv mast cells thiab basophils ua ib feem ntawm lub cev tiv thaiv kab mob hauv zos rau kev muaj lub cev invading.
Dab tsi yog hom loj ntawm histamine receptors lawv nyob qhov twg?
Histamine receptors yog G-protein coupled receptors nyob rau hauv the CNS, plawv, vasculature, ntsws, hnov qab, lub plab zom mov du, lub cev tsis muaj zog, thiabadrenal medulla