Cov lus xaus: Muaj kev sib cuam tshuam ntawm cephalosporins thiab penicillins; Cov neeg mob ua xua rau ntau yam penicillins yog ntau dua yuav ua rau muaj kev fab tshuaj rau cephalosporins; vim yog rhiab heev rau cov yam ntxwv zoo sib xws (nuclear thiab R1 sab-chain), penicillin-allergic cov neeg mob yuav tsim …
Tus neeg mob PCN puas tuaj yeem noj cov tshuaj cephalosporins?
… structurally related cephalosporins los yog carbapenems (monobactams [ie, aztreonam] tsis cross-reactive nrog penicillins thiab tuaj yeem muab kev nyab xeeb rau cov neeg mob penicillin-allergic).
Vim li cas thiaj yuav tsum tsis muab cephalosporin rau tus neeg mob uas tsis haum rau penicillin?
Cov neeg mob uas tau ntsib kev tsis haum rau IgE rau penicillin yuav tsum tsis txhob muab tshuaj rau cephalosporin vim qhov hnyav ntawm cov tshuaj tiv thaiv thiab muaj peev xwm ntawm cross-reactivity.
Yuav ua li cas cephalosporins muaj cross-reactivity nrog penicillin?
Cross-reactivity tau pom hauv 40 (19%) ntawm cov neeg mob. Tag nrho cov tshuaj tiv thaiv yog los ntawm peb lub cephalosporins nrog sab chains zoo ib yam li penicillin derivatives. Cefaclor thiab cephalexin muaj cov saw hlau zoo sib xws rau ampicillin thiab ua rau kev kuaj tawv nqaij zoo hauv 39 thiab 31 tus neeg mob, raws li.
Puas yog cephalosporins cuam tshuam nrog PCN?
Penicillins thiab cephalosporins yog ob hom tshuaj tua kab mob uas yog cov qauvzoo ib yam. Yog li ntawd, cov neeg uas muaj keeb kwm ntawm kev tsis haum tshuaj penicillin feem ntau nug seb lawv puas tuaj yeem noj cov tshuaj cephalosporin.
