C-reactive protein (CRP), tus cim ntawm qhov mob, yog qhov muaj peev xwm kwv yees ntawm CVD kev pheej hmoo, thiab statins txo CRP qib nce mus txog 60%. Kev txo qis CRP yog ywj siab ntawm LDL-C txo qis, thiab qhov sib txawv ntawm statins hauv kev txo qis CRP tuaj yeem ua qee lub luag haujlwm hauv CVD qhov txo qis.
YPob statins txo qhov mob hauv lub cev?
Statins kuj tseem muaj tshuaj tiv thaiv kab mob, suav nrog txo qis C-reactive protein (CRP) concentrations (1). Cov teebmeem ntawm kev txo qis lipoprotein tsawg (LDL) cov roj cholesterol nrog statins tuaj yeem ua rau muaj kev tiv thaiv kab mob vim tias LDL cov roj cholesterol nws tus kheej txhawb kev mob (2).
Cov tshuaj twg zoo tshaj rau siab CRP?
Cyclooxygenase inhibitors (aspirin, rofecoxib, celecoxib), platelet aggregation inhibitors (clopidogrel, abciximab), lipid lowering agents (statins, ezetimibe, fenofibrate, niacin, noj zaub mov), beta -adrenoreceptor antagonists thiab antioxidants (vitamin E), nrog rau angiotensin converting enzyme (ACE) inhibitors (ramipril, …
Puas atorvastatin txo CRP?
Atorvastatin 80 mg / hnub tau pom tias txo CRP concentration los ntawm 34-40% los ntawm qhov pibhauv cov neeg mob hyperlipidemia [14, 15], thiab 36.4% hauv cov neeg uas muaj Cov kab mob plawv uas muaj lipid profile ib txwm muaj [16]. Txog niaj hnub no, cov txheej txheem uas statins txo qis CRP concentrations tsis tau kawm hauv tib neeg.
Cov tshuaj dab tsi cuam tshuam rau CRPqib?
Qee cov tshuaj tuaj yeem ua rau koj qib CRP qis dua li qub. Cov no suav nrog cov tshuaj nonsteroidal anti-inflammatory (NSAIDs), aspirin, thiab steroids.
