Dab tsi yog qhov kev ua ntawm diphenolase ntawm nceb tyrosinase?

2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-02 15:51

Mushroom tyrosinase (EC 1.14. 18.1) catalyzes ob qho tib si hydroxylation ntawm tyrosine rau hauv o-diphenols thiab oxidation ntawm o-diphenols rau hauv o-quinones uas tsim xim av lossis xim dub.

YDiphenolase yog dab tsi?

18.1) yog multicopper monooxygenase enzyme nrog kev faib dav. Hauv cov tsiaj nyeg, nws yog lub luag haujlwm rau pigmentation ntawm daim tawv nqaij, qhov muag thiab plaub hau. Cov enzyme koom nrog rau qhov tsis xav tau browning ntawm nqaij tawv lossis txiav txiv hmab txiv ntoo thiab zaub.

Qhov tshwj xeeb ntawm tyrosinase yog dab tsi?

Kev ua haujlwm tshwj xeeb

Cov haujlwm tshwj xeeb ntawm tyrosinase yog 82 units/mg.

Yuav ua li cas tyrosinase inhibition kev ua haujlwm?

Tsis tas li ntawd, tyrosinase yog ib qho tseem ceeb ntawm cov enzyme uas tuaj yeem ua rau cov enzyme browning thiab melanin synthesis. … Tyrosinase inhibitors muaj peev xwm ntawm inhibiting biosynthesis ntawm melaninyog siv tam sim no hauv ntau yam hyperpigmentation thiab cosmetic agents los tswj kev tsim cov freckles [7, 8].

Y Yuav ua li cas hom inhibitor yog cinnamic acid ntawm tyrosinase?

Cinnamic (r), 4-hydroxycinnamic (p-coumaric), thiab 4-methoxycinnamic acids ua rau nce mus rau hom sib xyaw (kev sib tw / tsis sib tw) inhibition.

37 cov lus nug ntsig txog pom

Dab tsi yog qhov zoo tshaj plaws tyrosinase inhibitors?

YTyrosinase Inhibitors

• Hydroquinone - Muaj zog Tyrosinase Inhibitors. …
• Y Kojic Acid - lub ntuj siv lead ua zoo li cov khoom siv uas yog siv cov khoom siv tawv nqaij dawb. …
• Arbutin - glycosylated daim ntawv ntawm Hydroquinone tab sis maj mam, pom muaj nyob hauv Bearberry, Ntawv Mulberry, Blueberry thiab Cranberry.

Koj txo cov kev ua tyrosinase li cas?

Raws li tsab xov xwm 2017 hauv Phau Ntawv Xov Xwm ntawm Kev Kho Mob thiab Kev Zoo Nkauj Dermatology, vitamin C tuaj yeem txo cov haujlwm ntawm tyrosinase, uas tiv thaiv kev tsim ntawm melanin. Txawm hais tias nws muaj peev xwm los tiv thaiv pigmentation, kua txiv qaub tuaj yeem ua rau tawv nqaij. Siv tsuas yog thaum diluted thiab zam lub hnub tom qab siv.

Ib co tyrosinase inhibitors yog dab tsi?

Ntau tyrosinase inhibitors xws li hydroquinone (HQ) ^31– 34^{, arbutin, kojic acid}3537^{, azelaic acid 38}, ³⁹, L-ascorbic acid^{40 –42}, ellagic acid⁴³–45 ^{, tranexamic acid}46–48 ^{tau siv los ua cov tawv nqaij dawb, nrog qee qhov tsis zoo (Daim duab 3).}

Yuav ua li cas koj nres tyrosinase lawm?

Arbutin thiab hydroquinone tsuas yog tsis muaj zog tiv thaiv tib neeg tyrosinase nrog IC _{50 hauv millimolar ntau. Aurones (2-benzylidenebenzofuran-3(2H)-ones), ib txwm tshwm sim flavonoids ua inhibitors ntawm melanin biosynthesis hauv tib neeg melanocytes.}

Dab tsi yog qhov zoo tshaj ntawm daim tawv nqaij whitening agent?

Top 10 Safe Skin Lightening Ingredients

1. YKojic Acid. Feem ntau ua los ntawm cov khoom ntawm m alted nplej - uas yog sivua sake/rice wine, Kojic acid yog txhua yam-natural lightening thiab brightening skincare nquag. …
2. Vitamin C….
3. Alpha-arbutin. …
4. Niacinamide Niacinamide. …
5. Glutathione. …
6. Azelaic acid. …
7. YGlycolic acid. …
8. YLinoleic acid.

Ntawm pH twg yog tyrosinase nquag tshaj?

pH profile ntawm P. sanguineus CCT-4518 tyrosinase pom kev ua haujlwm zoo ntawm pH 6.6. Tyrosinase tau ua haujlwm ntau dua ntawm 45 ° C, txawm hais tias nws pom muaj kev ua haujlwm ntau dua li ntawm 40-60 ° C.

PH zoo tshaj rau tyrosinase yog dab tsi?

Nws kuj pom tias qhov zoo tshaj pH rau kev ua ntawm qos yaj ywm tyrosinase nyob ntawm pH 7.0-9.0, thiab qhov zoo tshaj plaws kub ntawm 35-40 ° C.

Qhov zoo tshaj pH ntawm tyrosinase yog dab tsi?

Cov purified tyrosinase tau ua kom zoo thiab cov txiaj ntsig tau qhia tias qhov zoo tshaj plaws yog pH 7.0 thiab kub 35 ° C. Qhov kev ua haujlwm siab tshaj plaws tau tshaj tawm rau nws cov khoom siv ntuj tsim, L-DOPA, nrog qhov pom tseeb Km tus nqi ntawm 0.933 mM.

Puas Thiamidol puas nyab xeeb?

Xaus: Thiamidol sawv cev muaj kev nyab xeeb thiab muaj txiaj ntsig zoo rau cov khoom lag luam kom zoo nkaujtawm tsam tom qab mob hyperpigmentation.

Yuav tiv thaiv melanogenesis li cas?

Ib qho tseem ceeb enzyme, tyrosinase , catalyzes thawj zaug thiab tsuas yog tus nqi txwv cov kauj ruam hauv melanogenesis, thiab kev txo qis ntawm cov enzyme kev ua haujlwm yog txoj kev tshaj tawm tshaj plaws rau kev txwv ntawm melanogenesis. Vim yog qhov teeb meem tseem ceeb ntawm cosmetic ntawm hyperpigmentation, muaj qhov xav tau loj rau melanogenesisinhibitors.

YPuas yog tyrosinase yog protein?

Tyrosinase-related protein, tseem hu ua catalase B thiab gp75, yog a melanocyte-specific protein uas nws cov haujlwm meej tsis nkag siab zoo. Ntau lub luag haujlwm yuav suav nrog kev ruaj khov tyrosinase, tswj melanin ntau lawm los ntawm cov qib peroxide, thiab txiav txim siab cov duab ntawm melanosomes.

Kuv tuaj yeem nce melanin hauv kuv lub cev li cas?

Koj tau txais vitamin A los ntawm cov zaub mov koj noj, tshwj xeeb tshaj yog zaub uas muaj beta carotene, xws li carrots, qos yaj ywm qab zib, spinach, thiab peas. Txij li thaum vitamin A kuj ua haujlwm ua antioxidant, qee cov kws tshawb fawb ntseeg tias cov vitamin no ntau dua li lwm yam, tej zaum yuav yog tus yuam sij rau melanin ntau lawm.

Yuav ua li cas cov tshuaj hormones ua rau cov tawv nqaij dawb?

Melanocyte-stimulating hormone piav qhia ib pawg ntawm cov tshuaj hormones tsim los ntawm pituitary caj pas, hypothalamus thiab cov hlwb ntawm daim tawv nqaij. Nws yog ib qho tseem ceeb rau kev tiv thaiv ntawm daim tawv nqaij los ntawm UV rays, kev loj hlob ntawm pigmentation thiab tswj qab los noj mov.

YKojic acid puas yog tyrosinase inhibitor?

Kojic acid (Daim duab 3a), qhov kev tshawb fawb ntau tshaj plaws inhibitor ntawm tyrosinase, yog cov kab mob fungal uas tam sim no siv los ua cov tshuaj pleev ib ce tawv nqaij-dawb thiab ua zaub mov ntxiv rau kev tiv thaiv enzymatic browning [25].

Yuav tshuaj dab tsi txo melanin?

Hydroquinone yog ib qho tshuaj depigmenting siv los ua kom pom qhov chaw ntawm cov tawv nqaij tsaus xws li freckles, hnub nyoog me ntsis, chloasma, thiab melisma tshwm sim los ntawm cev xeeb tub, tshuaj tiv thaiv kab mob, tshuaj hormone, lossis raug mob ntawm daim tawv nqaij. Hydroquinonetxo qhov tsim ntawm melanin hauv daim tawv nqaij.

Yuav ua li cas cov zaub mov txo melanin hauv qhov muag?

txiv kab ntxwv-xim txiv hmab txiv ntoo thiab zaub muaj ntau hauv beta-carotene, ib daim ntawv ntawm cov vitamin A uas pab nrog kev pom kev hmo ntuj, koj lub qhov muag muaj peev xwm kho qhov tsaus ntuj. Qhov ntawd yog yog rau qos yaj ywm qab zib, carrots, cantaloupe, mangos, thiab apricots (tseem tsis yog txiv kab ntxwv Starbursts thiab Lucozade, qab zib fiends). 2.

YPuas yog retinol yog tyrosinase inhibitor?

ATRA inhibited qhov kev qhia ntawm tyrosinase thiab TRP-1, thiab retinol inhibited qhov kev qhia ntawm tyrosinase, nyob rau hauv ib koob tshuaj.

Cov tshuaj tiv thaiv dab tsi yog catalyzed los ntawm tyrosinase?

Tyrosinase yog ib qho enzyme uas tswj hwm tus nqi txwv cov tshuaj tiv thaiv ntawm melanogenesis: nws catalyzes hloov dua siab tshiab ntawm phenol mus rau qhov sib thooj ortho-quinone. Streptomyces tyrosinase yog tsim raws li ib tug complex, nrog ib tug "caddie" protein uas pab thauj cov ob tooj liab ions mus rau hauv lub enzyme lub active chaw.

YPuas lactic acid inhibit tyrosinase?

Ntxiv rau, lactic acid inhibits melanin tsim los ntawm ncaj qha inhibiting tyrosinase kev ua haujlwm, cov nyhuv ywj pheej ntawm nws cov acidic xwm, uas txhais tau hais tias lactic acid cuam tshuam rau pigmentary lesions yog vim tsis yog xwb. Txhawm rau kom nrawm nrawm ntawm epidermal cell turnover, tab sis kuj ncaj qha inhibition ntawm melanin tsim hauv …