Acetylcholine esterase Acetylcholine esterase Enzyme qauv thiab cov txheej txheem
AChE yog hydrolase uas hydrolyzes choline esters. Nws muaj kev ua haujlwm siab catalytic-txhua lub molecule ntawm AChE degrades txog 25,000 molecules ntawm acetylcholine (ACh) ib ob, mus txog qhov txwv tso cai los ntawm diffusion ntawm substrate. https://en.wikipedia.org › wiki › Acetylcholinesterase
Acetylcholinesterase - Wikipedia
(AChE) inhibitors yog suav tias yog kev kho mob ntawm myasthenia gravis (MG). Edrophonium feem ntau yog siv los ua cov cuab yeej kuaj mob vim nws lub neej luv luv. Pyridostigmine Pyridostigmine Medication Summary
Tshuaj yog siv los tswj cov tsos mob thiab tswj kev tiv thaiv kab mob. Acetylcholine esterase (AChE) inhibitors raug suav hais tias yog kev kho mob yooj yim ntawm MG. Edrophonium feem ntau yog siv los ua cov cuab yeej kuaj mob vim nws lub neej luv luv. Pyridostigmine yog siv rau kev saib xyuas mus ntev. https://emedicine.medscape.com › article › 1171206-medication
Myasthenia Gravis Tshuaj: Anticholinesterase Inhibitors …
yog siv rau kev saib xyuas mus ntev.
Yuav ua li cas yog cov tshuaj xaiv rau myasthenia gravis?
Rituximab (Rituxan) thiab qhov tsis ntev los no tau pom zoo eculizumab (Soliris) yog cov tshuaj txhaj rau cov tshuaj myasthenia gravis. Cov tshuaj no yogfeem ntau yog siv rau cov neeg uas tsis teb rau lwm yam kev kho mob.
Dab tsi yog thawj kab kev kho mob rau myasthenia gravis?
Pyridostigmine. Thawj cov tshuaj siv rau myasthenia gravis feem ntau yog ib ntsiav tshuaj hu ua pyridostigmine, uas pab cov teeb liab hluav taws xob mus los ntawm cov hlab ntsha thiab cov leeg. Nws tuaj yeem txo cov leeg tsis muaj zog, tab sis cov nyhuv tsuas kav ntev li ob peb teev yog li koj yuav tsum tau noj nws ob peb zaug hauv ib hnub.
hom tshuaj twg yuav muaj txiaj ntsig zoo tshaj plaws hauv kev kho mob Alzheimer's kab mob thiab myasthenia gravis?
Acetylcholinesterase (AChE) inhibitors yog siv dav rau kev kho mob ntawm Alzheimer's kab mob thiab lwm yam dementias. Kev siv tsis ntev los no yog rau myasthenia gravis.
Yam tshuaj tua kab mob dab tsi yuav tsum zam hauv myasthenia gravis?
Cov tshuaj tua kab mob no muaj cov lus ceeb toom lub thawv dub thiab yuav tsum tsis txhob siv rau cov tib neeg uas muaj myasthenia gravis:
- Fluoroquinolones (Ciprofloxacin ("Cipro"), levofloxacin, gatifloxacin, femifloxacin, norfloxacin, ofloxacin)
- Ketek (telithromycin)
