Busulfan ua li cas nrog?

Cov txheej txheem:

Busulfan ua li cas nrog?
Busulfan ua li cas nrog?
Anonim

Busulfan yog alkylsulfonate. Nws yog tus neeg sawv cev alkylating uas tsim DNA-DNA interstrand crosslinks ntawm DNA bases guanine thiab adenine thiab nruab nrab ntawm guanine thiab guanine. Qhov no tshwm sim los ntawmSN2 cov tshuaj tiv thaiv uas cov nucleophilic guanine N7 tawm tsam cov pa roj carbon uas nyob ib sab ntawm mesylate tawm hauv pawg.

Dab tsi yog kev faib tshuaj rau busulfan?

Busulfan yog nyob rau hauv cov tshuaj hu ua alkylating agents. Nws ua haujlwm los ntawm kev qeeb lossis nres kev loj hlob ntawm cov qog nqaij hlav hauv koj lub cev.

Puas yog busulfan lom?

Busulfan yog thawj cov tshuaj cytotoxic tshaj tawm koom nrog kev mob ntsws ntsws [1]. Cov qauv qhia ntawm pulmonary toxicity muaj xws li mob ntsws mob, mob interstitial fibrosis, thiab alveolar hemorrhage.

Dab tsi yog qhov txiaj ntsig tseem ceeb ntawm busulfan?

Side Effects

Ntaus, ntuav, raws plab, cem quav, tsis qab los, qhov ncauj, mob plab / plab, kiv taub hau, o pob taws / taw / tes, dej ntws, mob taub hau, lossis teeb meem pw tsaug zog tuaj yeem tshwm sim. Yog tias ib qho ntawm cov teebmeem no tshwm sim los yog hnyav dua, qhia rau koj tus kws kho mob lossis tus kws muag tshuaj tam sim ntawd. Kev xeev siab thiab ntuav tuaj yeem hnyav.

Yam tshuaj busulfan hom kev ua yog dab tsi?

MECHANISM OF ACTION:

Busulfan yog bfunctional alkylating agent. 3-5 Tom qab lub cev nqus dej, carbonium ions tau tsim sai, ua rau alkylation ntawm DNA.

Pom zoo:

Nthuav cov khoom
Yuav tsum kho tus thawj coj yuav tsum hyphenated?
Nyeem ntxiv

Yuav tsum kho tus thawj coj yuav tsum hyphenated?

AP Cov Lus Qhia ntawm hyphenation ntawm lub npe Kev nkag mus rau hauv 2002 AP Stylebook hais txog lub hyphenating ntawm lub npe yog raws li nram no: " Editor in Chief: Ua raws li cov qauv ntawm kev tshaj tawm, tab sis feem ntau, tsis muaj hyphens.

Qhov hluav taws xob reverberating nyob qhov twg?
Nyeem ntxiv

Qhov hluav taws xob reverberating nyob qhov twg?

Hom kev rov qab rov qab no muaj nyob hauv qhov chaw ua pa ua pa Chaw ua pa Lub chaw ua pa yog tsim los ntawm peb pawg ua pa loj ntawm cov neurons, ob qho hauv medulla thiab ib qho hauv cov pons. … Lub chaw ua pa yog lub luag hauj lwm rau tsim thiab tswj lub suab ntawm kev ua pa, thiab kuj kho qhov no hauv homeostatic teb rau kev hloov ntawm lub cev.

Yuav tsum yog ntug dej hiav txwv sab hnub tuaj yuav tsum muaj peev txheej?
Nyeem ntxiv

Yuav tsum yog ntug dej hiav txwv sab hnub tuaj yuav tsum muaj peev txheej?

Thaum xa mus rau ib cheeb tsam tshwj xeeb, koj yuav tsum sau cov lus East Coast xws li "Kuv tabtom mus rau Sab Hnub Tuaj" vim "East Coast" yog lub npe tsim nyog hauv qhov no. Txawm li cas los xij, yog tias koj xa mus rau thaj chaw dav dav, xws li "