Gyrate Atrophy yog vim ntau yam hloov pauv hauv OAT noob, uas pom ntawm chromosome 10q26. Kev ua txhaum cai yog autosomal recessive. Ntau tshaj 50 qhov sib txawv tau raug txheeb xyuas, nrog kev hloov pauv tsis zoo tshwm sim feem ntau.
Dab tsi ua rau gyrate atrophy?
Mutations hauv OAT gene ua rau gyrate atrophy. OAT gene muab cov lus qhia ua rau cov enzyme ornithine aminotransferase. Cov enzyme no ua haujlwm nyob rau hauv cov chaw tsim hluav taws xob ntawm cov hlwb (mitochondria), qhov uas nws pab ua kom cov molecule hu ua ornithine.
Puas yog gyrate atrophy kho tau?
Gyrate atrophy yog ib yam kab mob uas tshwm sim los ntawm kev hloov pauv ntawm OAT noob. Cov neeg uas muaj gyrate atrophy feem ntau muaj qhov tsis pom kev hmo ntuj thiab qhov txhab ntawm lawv cov retinas. Cov kab mob no nce zuj zus mus rau lub sijhawm ua rau qhov pom kev thiab tuaj yeem ua rau qhov muag tsis pom. Tam sim no tsis muaj kev kho mob gyrate atrophy.
choroidal atrophy yog dab tsi?
Gyrate atrophy ntawm choroid thiab retina yog ib qho kev cuam tshuam ntawm cov protein metabolism uas ua rau pom kev tsis pom kev zoo. Cov tsos mob xws li pom ze ze (myopia), pom teeb meem hauv qhov tsis pom kev (qhov muag tsis pom kev hmo ntuj), thiab tsis pom kev sab (peripheral) pom thaum yau.
Cov tsos mob ntawm gyrate atrophy yuav txo qis li cas?
Kev kho mob ntawm gyrate atrophy muaj xws li txo cov substrate arginine, los ntawm qhov twg ornithine yogtsim , lossis nce kev ua haujlwm ntawm OAT enzyme los ntawm kev muab ntau cofactor vitamin B6.
