Exotoxins yog ib pawg ntawm cov proteins uas muaj kuab lom uas tau zais los ntawm cov kab mob, nkag mus rau hauv cov cell, thiab catalyze cov kev hloov kho covalent ntawm cov khoom siv ntawm tes los hloov cov tswv tsev cell physiology. Ob leeg Gram-negative thiab Gram-positive bacteria tsim exotoxins.
Puas yog endotoxin gram-zoo lossis tsis zoo?
Endotoxins yog glycolipid, LPS macromolecules uas tsim txog li 75% ntawm daim nyias nyias ntawm gram-negative cov kab mob uas muaj peev xwm ua rau tuag taus.
YPuas yog exotoxin A polypeptide?
Diphtheria toxin yog a polypeptide nrog qhov hnyav molecular ntawm kwv yees li 58,000 Da. Cov tshuaj lom yog secreted raws li ib tug proenzyme, yuav tsum tau enzymatic cleavage rau hauv ob feem (fragments A thiab B) ua active.
YPuas Protein A yog exotoxin?
Exotoxins feem ntau yog proteins, tsawg kawg nkaus polypeptides, uas ua rau enzymatically lossis los ntawm kev ua ncaj qha nrog cov tswv tsev thiab txhawb ntau hom lus teb. Feem ntau exotoxins ua rau ntawm cov ntaub so ntswg nyob deb ntawm qhov qub ntawm cov kab mob nkag los yog kev loj hlob.
peb hom exotoxins yog dab tsi?
Muaj peb hom exotoxins:
- superantigens (Hom I co toxins);
- exotoxins uas ua rau cov cell membranes (Tom II co toxins); thiab.
- A-B co toxins thiab lwm yam tshuaj lom uas cuam tshuam nrog kev ua haujlwm ntawm tes (hom III co toxins).