Cov kua qaub conjugate (protonated daim ntawv) ntawm imidazole sab saw hauv histidine muaj pKa ntawm kwv yees li 6.0. Yog li, hauv qab pH ntawm 6, lub nplhaib imidazole feem ntau yog protonated (raws li tau piav qhia los ntawm Henderson-Hasselbalch equation). Lub nplhaib ua rau imidazolium dais ob daim NH daim ntawv cog lusthiab muaj tus nqi zoo.
Vim li cas histidine thiaj li raug nqi pH 7?
Ntawm pH=7.8, cov histidines yuav muaj qhov nruab nrab ntawm cov saw hlau sab nraud thiab yog li cov polypeptide yuav tsis soluble hauv H2O dua li ntawm pH 5.5, qhov twg histidines yuav muaj cov txiaj ntsig zoo. … Ntawm pH 7, Arg muaj cov kab txuas sab nraud tag nrho thiab muaj peev xwm ua tau tsuas yog tus neeg pub nyiaj hydrogen xwb (saib Stryer, p. 33).
Histidine puas tuaj yeem raug nqi zoo?
Histidine, lysine, thiab arginine muaj cov saw hlau yooj yim, thiab side saw hauv tag nrho peb yog raug them zoo ntawm qhov nruab nrab pH.
Vim li cas histidine tseem ceeb?
Qhov no yog vim lawv muaj tag nrho cov nqi ntawm lawv cov pab pawg ntawm pawg ntawm lub cev pH. … Histidine kuj suav hais tias yog qhov yooj yim tab sis nws tuaj yeem muaj qhov zoo lossis qhov nruab nrab ntawm nws cov pab pawg sab nraud ntawm lub cev pH. Qhov no yog vim histidine's side chain muaj pKa tus nqi ntawm 6.0.
Histidine siv rau dab tsi?
Histidine yog ib qho amino acid feem ntau cov neeg tau txais los ntawm cov khoom noj. Nws tau siv hauv kev loj hlob, kho cov ntaub so ntswg puas, thiab ua cov qe ntshav. Nws pabtiv thaiv cov paj hlwb. Nws tau siv los ntawm lub cev los ua cov tshuaj histamine.
