2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
In hereditary retinoblastoma, mutations in the RB1 gene like to be inherited in an autosomal dominant pattern. Autosomal dominant qub txeeg qub teg txhais tau hais tias ib daim qauv ntawm cov noob hloov pauv hauv txhua lub xov tooj yog txaus los ua kom muaj kev pheej hmoo mob qog noj ntshav.
Puas yog retinoblastoma yog ib yam kab mob caj ces?
Puas retinoblastoma tuaj yeem tau txais txiaj ntsig? Kwv yees li 40 feem pua ntawm cov menyuam yaus uas muaj retinoblastoma muaj ib hom kab mob tshwm sim. Qee cov menyuam yaus uas muaj keeb kwm retinoblastoma tau txais kev hloov pauv ntawm RB1 los ntawm niam txiv uas muaj retinoblastoma thaum nws tseem yog menyuam yaus.
Yam hloov pauv dab tsi ua rau retinoblastoma?
Heritable or bilateral retinoblastoma
Hais txog 1 ntawm 3 tus menyuam yaus uas muaj retinoblastoma muaj ib cov kab mob hloov pauv hauv ib lub noob RB1; uas yog, RB1 noob hloov pauv nyob rau hauv tag nrho cov hlwb hauv lub cev. Hauv feem ntau ntawm cov menyuam yaus no (75%), qhov kev hloov pauv no tshwm sim thaum ntxov hauv kev loj hlob, thaum tseem nyob hauv plab.
Thaum twg yog lub hauv paus caj ces ntawm retinoblastoma thawj zaug?
Tus qauv ua haujlwm ntawm cov qog qog qog ntshav tau thawj zaug los ntawm Alfred Knudson hauv xyoo 1970s uas tau piav qhia meej txog cov txheej txheem ntawm retinoblastoma. Yog tias ob leeg alleles ntawm cov noob no tau hloov pauv, cov protein tsis ua haujlwm thiab qhov no ua rau muaj kev loj hlob ntawm retinoblastoma.
retinoblastoma yog dab tsi thiab nws lub hauv paus caj ces yog dab tsi?
Retinoblastoma yog tshwm sim los ntawm hloov pauv (mutations) hauv retinoblastoma 1 (RB1) noob hauv retinoblasts. Cov kev hloov pauv no ua rau retinoblasts loj hlob ntawm kev tswj hwm thiab tsim cov qog hu ua retinoblastoma. Muaj 2 daim ntawv theej ntawm RB1 noob hauv txhua lub cell.
Pom zoo:
Vim li cas mob qog noj ntshav suav tias yog kab mob sib kis?
Txawm tias mob qog noj ntshav nws tus kheej tsis kis tau, muaj qee cov kab mob uas tuaj yeem ua lub luag haujlwm hauv kev txhim kho qee yam mob qog noj ntshav. Qhov no tuaj yeem ua rau qee tus neeg xav tsis ncaj ncees tias "mob qog noj ntshav tau ntes.
Cov kab kab kab kab kab ua kab mob txaus ntshai npaum li cas?
Nyob rau hauv peb thiab tom ntej instars ntawm lawv txoj kev loj hlob, Pine processionary caterpillars yog mob heev rau daim tawv nqaij ntawm tib neegthiab lwm yam tsiaj. Kev sib cuag yooj yim nrog cov plaub hau ntawm kab ntsig tuaj yeem ua rau pob khaus hnyav (urticaria) thiab khaus qhov muag, thiab qee tus neeg yuav muaj kev fab tshuaj.
Puas lamellar ichthyosis yog ib yam kab mob caj ces?
Lamellar ichthyosis (LI) yog ib yam tsis tshua muaj kab mob ntawm daim tawv nqaij uas tshwm sim thaum yug . Nws yog ib qho ntawm peb kab mob ntawm daim tawv nqaij hu ua autosomal recessive congenital ichthyoses (ARCI). Lwm ob lub npe hu ua harlequin ichthyosis harlequin ichthyosis Ichthyosis congenita (collodion baby;
Lub sijhawm suav suav suav suav suav cov neeg txawv tebchaws?
Puas yog cov neeg tuaj txawv teb chaws tsis raug tso cai suav nrog cov neeg nyob hauv suav? Yog, txhua tus neeg (cov pej xeem thiab cov neeg tsis yog pej xeem) uas muaj chaw nyob ib txwm nyob hauv Tebchaws Meskas suav nrog cov neeg nyob hauv kev suav pej xeem.
Puas yog tshuaj tua kab mob suav tias yog tshuaj tua kab mob?
Note: tshuaj tiv thaiv kab mob sib txawv rau cov tshuaj tua kab mob, uas yog tshuaj tua kab mob. Cov tshuaj tua kab mob tsis tua cov kab mob - lawv tua lwm hom kab mob (hu ua kab mob). Qhov tseeb, koj yuav kis tau tus kab mob fungal ntau dua yog tias koj noj tshuaj tua kab mob.
