Cov tshuaj twg yog bacteriostatic inhibitors ntawm protein synthesis?

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Cov tshuaj twg yog bacteriostatic inhibitors ntawm protein synthesis?
Cov tshuaj twg yog bacteriostatic inhibitors ntawm protein synthesis?
Anonim

Bacteriostatic protein-synthesis inhibitors uas tsom rau ribosome, xws li tetracyclines thiab gly-cylcyclines, chloramphenicol, macrolides thiab ketolides, lincosamides (clindamycin), streptogramins (quinupristin / dalfopristin), oxazolidinones (linezolid), thiab aminocyclitols (spectinomycin).

Vim li cas protein synthesis inhibitors yog bacteriostatic?

Chloramphenicol yog ib qho bacteriostatic protein synthesis inhibitor. Nws nkag mus rau cov kab mob ntawm tes los ntawm kev yooj yim diffusion. Nws khi rov qab mus rau 50S ribosomal subunit nyob ze ntawm qhov chaw khi rau cov tshuaj tua kab mob macrolide thiab clindamycin. Yog li, cov tshuaj no thaum muab concurrently tuaj yeem cuam tshuam rau ib leeg kev ua.

Qhov twg hauv qab no yog ib qho piv txwv ntawm cov tshuaj bacteriostatic uas inhibits protein synthesis los ntawm kev thaiv cov translocation ntawm polypeptide?

Macrolides yog dav-spectrum, bacteriostatic tshuaj uas thaiv elongation ntawm cov proteins los ntawm inhibiting peptide daim ntawv cog lus ntawm kev sib txuas ntawm cov amino acids. Thawj macrolide yog erythromycin. Nws raug cais tawm xyoo 1952 los ntawm Streptomyces erythreus thiab tiv thaiv kev hloov pauv.

Yuav ua li cas cov tshuaj tua kab mob inhibits protein synthesis hauv cov kab mob?

Streptomycin, ib qho ntawm feem ntau siv aminoglycosides, cuam tshuam nrog kev tsim ntawm 30S kev pib ua haujlwm. Kanamycin thiabtobramycin kuj khi rau 30S ribosome thiab thaiv kev tsim ntawm qhov loj dua 70S pib ua haujlwm.

Cov tshuaj tiv thaiv kab mob twg inhibit protein synthesis?

Clindamycin . Linezolid (ib oxazolidinone) Macrolides. Telithromycin.

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