Yog C-3 txoj haujlwm nyob, ces electrophilic hloov chaw yuav tshwm sim ntawm C-2 thiab yog tias ob leeg tau nyob ces electrophile tawm tsam ntawm C-6 txoj haujlwm. 3.1. 1 Protonation: Indole yog lub hauv paus tsis muaj zog pKa -3.5. Cov nitrogen atom ntawm indole tau yooj yim protonated txawm nyob rau hauv dej (ntawm pH=7) muab 1H-indolium cation.
Vim li cas electrophilic hloov ntawm indole tshwm sim ntawm C 3?
Txoj haujlwm reactive tshaj plaws tam sim no nyob rau hauv indole nplhaib yog thib peb carbon. Qhov no yog ntau reactive ntawm electrophilic hloov cov tshuaj tiv thaiv thiab nws yog heev reactive tshaj benzene. Lub Vilsmeier-Haack formylation tuaj yeem tshwm sim ntawm qhov chaw thib peb ntawm indole. …
txhais li cas los ntawm electrophilic nres?
Electrophilic hloov pauv cov tshuaj tiv thaiv yog cov tshuaj tiv thaiv uas ib qho electrophile tshem tawm cov pab pawg ua haujlwm hauv cov khoom sib xyaw, uas feem ntau, tab sis tsis tas li, hydrogen atom. … Qee cov aliphatic tebchaw tuaj yeem hloov pauv electrophilic ib yam nkaus.
Nyob rau hauv txoj hauj lwm ntawm anthracene puas electrophilic nres feem ntau ruaj khov thiab vim li cas?
Nyob rau hauv feem ntau lwm cov tshuaj tiv thaiv ntawm anthracene, lub nplhaib hauv nruab nrab kuj tau tsom, vim nws yog qhov muaj zog tshaj plaws. Electrophilic hloov pauv tshwm sim ntawm "9" thiab "10" txoj haujlwm ntawm lub nplhaib nruab nrab, thiab oxidation ntawm anthracene tshwm sim tau yooj yim, muab anthraquinone, C14H8O2 (hauv qab).
IbTxoj hauj lwm twg ntawm quinoline nucleophilic hloov pauv tshwm sim?
Quinoline kuj tau txais kev hloov pauv nucleophilic. Kev hloov pauv tshwm sim ntawm C-2 (los yog ntawm C-4 yog C-2 raug thaiv).
