Cov kev ntsuam xyuas tus cwj pwm pom tau tias bergapten tiv thaiv kev nco tsis taus vim yog kev tswj hwm ntawm scopolamine. Cov teebmeem pom tau tshwm sim los ntawm inhibition ntawm acetylcholinesterase kev ua haujlwm hauv hippocampus thiab prefrontal cortex. Tsis tas li ntawd, bergapten ua rau muaj kev cuam tshuam oxidative tseem ceeb.
Puas scopolamine ua rau nco tsis tau?
Scopolamine yuav ua rau tsaug zog, ua rau lub sijhawm tsis nco qab, kev puas siab puas ntsws lom (hallucinations, tsis meej pem, tsis meej pem, confabulation), mob lub kaum sab xis kaw glaucoma, lossis tso zis tso rau hauv cov neeg raug mob., tshwj xeeb tshaj yog cov laus.
Scopolamine cuam tshuam li cas rau kev nco?
Nws kuj tau tshaj tawm tias cholinergic blockade los ntawm scopolamine ua rau muaj kev nco tsis zoo thiab cuam tshuam nrognce latency, nrog rau kev txo qis lossis tshem tawm ntawm lub suab P3, yog li txhawb kev xav txog kev sib txuas ntawm P3 thiab lub cim xeeb ntev ua haujlwm.
Scopolamine ua rau amnesia li cas?
Scopolamine yog muscarinic ACh receptor antagonist uas tuaj yeem ua rau kev kawm thiab kev nco tsis txaus los ntawm cuam tshuam cholinergic neurotransmission; Cov tshuaj no tau siv los ua kom amnesia hauv kev sim murine qauv [14].
Puas scopolamine ua rau dementia?
Scopolamine-induced dementia ho nce hlwb cov ntsiab lus ntawm 5-HT, NA thiab DA los ntawm 38.56%, 33.75% thiab 32.98%,raws li piv nrog rau ib txwm pab pawg neeg. Donepezil txo qis 5-HT, NE thiab DA lub hlwb cov ntsiab lus los ntawm 16.04%, 36.16% thiab 23.98%, raws li piv nrog scopolamine tswj pawg (Fig.
