Large granular lymphocytes (LGLs) yog loj lymphocytes nrog puag ncig lossis reniform nuclei, dav cytoplasm, thiab azurophilic granules hauv lawv cytoplasm(Fig. 1) (1). Lawv suav txog 10-15% ntawm peripheral ntshav mononuclear hlwb.
Puas loj cov lymphocytes zoo li qub?
Large Granular Lymphocytes
LGLs sawv cev rau cov neeg tsawg, xws li ntawm 2 txog 15%, ntawm tib neeg peripheral ntshav lymphocytes.
Dab tsi ua rau cov qog ntshav qog ntshav loj?
Log granular lymphocyte leukemia tshwm sim los ntawm muaj ntau LGLs hauv koj cov ntshav; txawm tias LGLs ntau dua li qub, lossis feem pua siab dua piv rau lwm hom qe ntshav dawb.
Puas yog loj granular lymphocytosis cancer?
Large granular lymphocyte (LGL) leukemia yog ib yam mob qog nqaij hlav dawb cov qe ntshav hu ua lymphocytes, uas tshwm sim hauv cov qog ntshav thiab cov pob txha thiab pab tiv thaiv kab mob.
cov lymphocytes loj ua dab tsi?
NK hlwb yog cov qog ntshav loj loj uas tsis tshwj xeeb tua cov kab mob kis kab mob thiab qog hlwb. NK hlwb yog cov tswj hwm kev tiv thaiv kab mob. Kev tua los ntawm NK hlwb yog txhim kho los ntawm cytokines xws li IFN-α, IFN-β, thiab IL-12, thiab kev ua kom muaj zog ntxiv tuaj yeem tshwm sim nyob rau hauv lub xub ntiag ntawm activated T cells.