2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Puas yog dysplastic nevus hloov mus ua melanoma? Yog, tab sis feem ntau dysplastic nevi tsis tig mus rau hauv melanoma(1, 3). Feem ntau nyob ruaj khov nyob rau lub sijhawm.
Ntau npaum li cas dysplastic nevus tig mus ua melanoma?
Cov kws sau ntawv kwv yees tias qhov hloov pauv txhua xyoo ntawm ib qho nevus rau hauv melanoma yog li ntawm ≤1 ntawm 200,000 rau cov txiv neej thiab cov poj niam hnub nyoog qis dua 40 xyoo mus rau kwv yees 1 ntawm 33,000 rau cov txiv neej laus dua 60 xyoo.
% pes tsawg ntawm dysplastic nevus dhau los ua melanoma?
Lub koom haum ntawm dysplastic nevi nrog melanoma tau tshaj tawm, txawm tias tsis muaj kev txheeb xyuas los ntawm qib ntawm atypia. Kev tshawb fawb tau kwv yees tias 60% mus rau 80% ntawm melanomas tshwm sim de novo12 thiab cov melanomas tshwm sim nrog ib qho atypical nevus hauv 0.5% rau 46% ntawmcase.
Koj tuaj yeem qhia melanoma los ntawm dysplastic nevi li cas?
Ib txhia dysplastic nevi qhia cov cim ceeb toom ntawm melanoma: khaus, nce, crusting, oozing, xim xiav-dub, mob, los ntshav, o thiab ulceration. Yog tias ib qho ntawm cov cim ceeb toom no tshwm sim rau ntawm koj tus kheej daim tawv nqaij lossis ntawm ib tug phooj ywg lossis cov neeg hauv tsev neeg, sab laj nrog kws kho hniav tam sim ntawd.
Nevus tuaj yeem ua rau melanoma?
Nevi kuj tseem yog qhov tseem ceeb raws li qhov muaj peev xwm ua ntej ntawm melanoma; Txawm li cas los xij, feem ntau nevi yog qhov ruaj khov thiab yuav tsis nce mus rau qhov tsis zoo.
Pom zoo:
Dab tsi yog qhov hloov pauv thiab hloov pauv hloov pauv?
Point mutations hloov ib leeg nucleotide. Frameshift kev hloov pauv yog ntxiv lossis tshem tawm ntawm nucleotides uas ua rau muaj kev hloov pauv hauv kev nyeem ntawv. frameshift thiab point mutation yog dab tsi? Ib qho kev hloov pauv cuam tshuam rau ib khub hauv paus.
Qhov kev hloov pauv no puas yuav ua rau muaj kev hloov pauv hloov pauv?
Yog li, yog tias muaj kev hloov pauv, piv txwv li, kev ntxig lossis tshem tawm ntawm nucleotide, tshwm sim, qhov no tuaj yeem ua rau kev hloov pauv ntawm kev nyeem ntawv. Nws hloov tag nrho cov amino acid ib ntus. Cov kev hloov pauv no yog hu ua frameshift mutation (tseem hu ua kev nyeem ntawv hloov pauv, nyeem ntawv hloov pauv, lossis framing yuam kev).
Puas yog jurassic ntiaj teb hloov pauv hloov pauv hloov pauv?
Qee zaum, paub meej, koj yuav tau rov qab mus rau lub sijhawm dhau los - txuag manually, thiab feem ntau, raws li game's autosave yog… tsis zam txim - tab sis feem ntau ntawm cov lub sijhawm koj tuaj yeem khaws cov khoom thiab khaws cia nrog.
Qhov twg yog qhov kev hloov pauv hloov pauv hloov pauv?
Semiconservative replication piav qhia txog cov txheej txheem ntawm DNA replication nyob rau hauv tag nrho cov paub hlwb. DNA replication tshwm sim ntawm ntau lub hauv paus pib ntawm kev rov ua dua raws DNA qauv strand. Raws li DNA ob chav helix yog unwound by helicase, replication tshwm sim nyias ntawm txhua tus qauv strand nyob rau hauv antiparallel cov lus qhia.
Qhov kev hloov pauv twg yog xav tias yuav cuam tshuam los ntawm kev hloov pauv hloov pauv?
Dependent Variable Qhov sib txawv uas nyob ntawm lwm yam uas ntsuas. Cov kev hloov pauv no yuav tsum tau hloov pauv raws li qhov kev sim ua haujlwm ntawm tus kheej hloov pauv lossis hloov pauv. Nws yog cov nyhuv presumed. Qhov kev tshawb fawb hloov pauv twg yog qhov tshwm sim?
