Cov cytoskeletons ntawm cov leukocytes yog reorganized nyob rau hauv xws li ib tug txoj kev uas cov leukocytes kis tawm thoob plaws lub endothelial hlwb. Nyob rau hauv daim ntawv no, leukocytes txuas pseudopodia thiab dhau los ntawm khoob ntawm cov hlwb endothelial. Qhov kev hla ntawm cov hlwb los ntawm cov phab ntsa ntawm cov hlab ntsha tsis zoo yog hu ua diapedesis.
leukocytes ua diapedesis nyob qhov twg?
TEM, lossis diapedesis, yog cov txheej txheem uas cov leukocyte squeezes hauv ameboid zam hla cov hlwb endothelial. Qhov no yuav luag ib txwm tshwm sim ntawm endothelial cell ciam teb101, 117(ib feem me me ntawm kev hloov pauv tshwm sim los ntawm lub cev endothelial; qhov no yuav tham tom qab).
Yuav ua li cas leukocytes migrate?
Vim leukocytes tsis tuaj yeem ua luam dej, lawv raug xaiv hauv zos ntawm qhov chaw mob hauv cov txheej txheem nplaum uas tso cai rau lawv txuas rau phab ntsa ntawm lub nkoj, locomote raws phab ntsa mus rau cov ciam teb endothelial, hla lub endothelium thiab subendothelial. Hauv qab daus daim nyias nyias, thiab tsiv teb tsaws dhau ntawm qhov sib cuam tshuam …
leukocytes paub qhov twg mus?
Leukocytes muaj cov receptors nyuaj heev uas tso cai rau lawv nkag siab cov gradients sib txawv. Leukocytes, kuj, cia siab rau cov scaffolds tshwj xeeb hauv txhua cov ntaub so ntswg kom yooj yim mus ncig-hauv cov qog ntshav, siab, ntsws, tawv nqaij, thiab lub hlwb. Leukocytes paub tawm hauv cov hlab ntsha mus rau qhov kev coj uakab mob.
Dab tsi yog kauj ruam thib ob hauv diapedesis ntawm cov qe ntshav dawb?
kauj ruam thib ob yuav tsum lub tethered leukocyte los ua haujlwm, txheej txheem kho los ntawm chemokines thiab lwm yam tshuaj lom neeg. Cov neeg nruab nrab no nce integrin adhesiveness los ntawm augmented receptor affinity thiab mobilization ntawm integrin los ntawm cellular khw.
