Concanavalin A yog lectin Ameslikas muab rho tawm los ntawm jack-bean. Nws yog ib tug tswv cuab ntawm tsev neeg legume lectin. Nws khi tshwj xeeb rau qee cov qauv pom muaj nyob hauv ntau cov suab thaj, glycoproteins, thiab glycolipids, feem ntau yog sab hauv thiab tsis txo qis α-D-mannosyl thiab α-D-glucosyl pawg.
txhais li cas los ntawm concanavalin?
: a protein uas tshwm sim hauv cov taum jackthiab yog mitogen thiab hemagglutinin.
Puas yog concanavalin tshuaj?
Concanavalin A (ConA), a lectin nrog mannose tshwj xeeb uas tuaj yeem ua rau mob siab mob siab, tau sim rau nws txoj kev kho mob tiv thaiv kab mob siab. ConA yog cytotoxic lossis inhibitory rau hepatoma hlwb, uas yog kho los ntawm txoj kev autophagic los ntawm mitochondria.
YPuas yog concanavalin A toxin?
Qhov cuam tshuam ntawm qhov sib ntxiv ntawm cov cellular ntxiv ntawm cov protein ib txwm, oligomers thiab cov fibrils paub tab tau kuaj ntawm LAN5 neuroblastoma hlwb los ntawm MTS kev soj ntsuam. … Qhov no tshwm sim vim lawv raug recruited nyob rau hauv mature fibrillar qauv uas-raws li ib tug tshwm sim-tawm mus rau non-toxic.
Dab tsi yog qab zib khi rau?
Cov ntsiab lus carbohydrate-binding tshwj xeeb ntawm Con A tau kawm paub meej los ntawm txhua qhov kev xav tau. Nws khi d-glucose, d-fructose, d-mannose, N- acetyl-d-glucosamine thiab lwm yam monosaccharides [3, 8], α-anomer ntawm d-mannose yog cov monosaccharide feem ntau ntxiv rau Con A qab zibbinding site.