Heparin tau tshem tawm nrog ib nrab lub neej ntawm 60 txog 90 feeb nyob rau hauv ib qho kev tsis sib xws los ntawm ob qho tib si nrawm thiab qeeb. Qhov ceev thiab saturable mechanism ntawm heparin clearance yog feem ntau vim yog kev khi ntawm cellular receptors, qhov twg nws yog internalized thiab degraded.
Nws siv sijhawm ntev npaum li cas rau heparin hnav?
Txawm hais tias cov metabolism ntawm heparin yog complex, nws yuav, rau lub hom phiaj ntawm kev xaiv ib koob tshuaj protamine, xav tias yuav muaj ib nrab-lub neej ntawm kwv yees 1/2 teev tom qab txhaj tshuaj.
Ib nrab-lub neej ntawm heparin yog dab tsi thaum muab IV?
Lub neej ib nrab (t 1/2) ntawm heparin yogtxog 1.5 teev. Tab sis nws anticoagulation ib nrab-lub neej tsis cuam tshuam nrog nws cov concentration ib nrab-lub neej. Heparin tuaj yeem ua sai sai tom qab kev tswj hwm IV lossis ua tsis pub dhau 1 teev tom qab kev tswj hwm SC.
Ib nrab-lub neej ntawm heparin ntev npaum li cas?
Yog li, qhov pom tseeb ib nrab ntawm lub neej ntawm heparin nce ntawm ≈30 feeb tom qab IV bolus ntawm 25 U / kg rau 60 feeb nrog IV bolus ntawm 100 U / kg thiab 150 feeb nrog bolus ntawm 400 U / kg.
Ib nrab-lub neej ntawm UFH yog dab tsi?
Lub plasma ib nrab-lub neej ntawm UFH yog kwv yees li 30 txog 90 feeb hauv cov neeg laus noj qab haus huv; Txawm li cas los xij, ib nrab-lub neej yog koob tshuaj nyob ntawm thiab nce nrog nce koob.
