Introduction: Denaturation ntawm cov proteins cuam tshuam kev cuam tshuam thiab kev puas tsuaj ntawm ob qho tib si theem nrab thiab qib theem. Txij li thaum cov tshuaj tiv thaiv denaturation yog tsis muaj zog txaus los tawgcov peptide daim ntawv cog lus, cov qauv tseem ceeb (ib ntu ntawm cov amino acids) tseem zoo ib yam tom qab txheej txheem denaturation.
Yuav tsis cuam tshuam dab tsi thaum muaj protein ntau?
Denatured proteins poob lawv cov qauv 3D thiab yog li tsis tuaj yeem ua haujlwm. Protein folding yog qhov tseem ceeb ntawm seb lub globular lossis membrane protein tuaj yeem ua nws txoj haujlwm kom raug; nws yuav tsum tau muab tais rau hauv txoj cai zoo los ua haujlwm.
Dab tsi cuam tshuam rau cov protein denaturation?
Hloov pauv hauv pH, Kub nce, raug UV lub teeb / hluav taws xob (dissociation of H bonds), Protonation amino acid residues, ntsev ntau ntauyog cov ntsiab lus tseem ceeb uas ua rau muaj kev puas tsuaj rau lub cev. protein rau denature.
YYuav ua li cas thaum cov protein yog denatures?
Denaturation koom nrog kev tawg ntawm ntau qhov kev sib txuas tsis muaj zog, lossis kev sib cog lus (piv txwv li, hydrogen bonds), nyob rau hauv ib qho protein molecule uas yog lub luag haujlwm rau cov qauv ntawm cov protein ntau. nyob rau hauv nws natural (native) xeev. Denatured proteins muaj ib tug looser, ntau random qauv; feem ntau yog insoluble.
4 yam uas ua rau cov protein denaturation yog dab tsi?
Ntau yam ua rau muaj cov protein ntau. Ib txhia ntawm lawv yog ib tugnce kub uas ruptures cov protein molecules ' qauv, hloov pH theem, ntxiv cov hlau hnyav ntsev, acids, hauv paus, protonation ntawm amino acid residues, thiab raug UV teeb thiab hluav taws xob.
