Lub hom phiaj tshuaj tua kab mob twg yog folate synthesis?

Cov txheej txheem:

Lub hom phiaj tshuaj tua kab mob twg yog folate synthesis?
Lub hom phiaj tshuaj tua kab mob twg yog folate synthesis?
Anonim

Sulfonamides thiab trimethoprim tsom rau folic acid biochemical txoj hauv kev ntawm cov kab mob. Cov tshuaj tua kab mob no yog hu ua folic acid pathway inhibitors. Sulfonamides cuam tshuam nrog kev tsim ntawm folic acid, ib qho tseem ceeb precursor rau nucleic acid synthesis.

Yuav ua li cas cov tshuaj tua kab mob hauv qab no yog folate synthesis inhibitor?

5.2 Trimethoprim . TMP yog cov tshuaj tua kab mob hluavtaws uas khi nrog cov enzyme dihydrofolate reductase (DHFR) inhibiting folic acid synthesis pathway (Brogden li al., 1982). Nws yog dav siv nyob rau hauv kev kho mob ntawm urinary kab mob thiab Pneumocystis jiroveci pneumonia.

Yuav tshuaj pab pawg twg inhibits folic acid synthesis?

Sulfonamides, chav kawm ntawm cov tshuaj tua kab mob uas ua haujlwm los ntawm inhibiting folate biosynthesis.

YFolate synthesis yog dab tsi?

Folic acid yog ib qho khoom noj tseem ceeb tsim nyog rau cov protein thiab nucleic acid synthesis(DNA thiab RNA). Folic acid yog tsim los ntawm cov kab mob los ntawm substrate, para-amino-benzoic acid (PABA), thiab tag nrho cov hlwb xav tau folic acid rau kev loj hlob. Folic acid (raws li vitamin nyob rau hauv cov zaub mov) diffuses los yog raug thauj mus rau hauv mammalian hlwb.

Cov tshuaj twg raug cais ua cov tshuaj folate antagonists?

Ntau cov tshuaj xws li aminopterin, methotrexate (amethopterin), pyrimethamine, trimethoprim thiab triamterene ua raws li cov tshuaj tiv thaiv folate thiab tsim cov folate.deficiency los ntawm inhibiting no enzyme.

Pom zoo:

Nthuav cov khoom
Pob splanchnic paj hlwb synapse?
Nyeem ntxiv

Pob splanchnic paj hlwb synapse?

Cov hlab ntsha loj dua splanchnic taug kev los ntawm diaphragm thiab nkag mus rau hauv plab kab noj hniav. Nws fibers synapse ntawm celiac ganglia. Cov hlab ntsha txhawb nqa rau lub celiac plexus, lub network ntawm cov hlab ntsha nyob rau thaj tsam ntawm qhov chaw ntawm lub cev celiac ceg ntawm lub plab aorta.

Yuav coreopsis puas tawg rau lub caij ntuj sov?
Nyeem ntxiv

Yuav coreopsis puas tawg rau lub caij ntuj sov?

yog qhov kev xaiv zoo meej. Nrog ntau tshaj 80 hom coreopsis, muaj ntau yam kom haum txhua lub vaj tsim. Haiv neeg rau North America, coreopsis nroj tsuag loj hlob nyob rau hauv upright clumps thiab feature masses ntawm kaj, showy, daisy-zoo li paj thoob plaws lub caij ntuj sov.

Lub ntsiab lus ntawm kev hush up yog dab tsi?
Nyeem ntxiv

Lub ntsiab lus ntawm kev hush up yog dab tsi?

: tsi ntsiag to kuv hais rau nws kom txhob maj. slang txhais li cas? Koj hais 'Hush! ' rau ib tug thaum koj nug lossis qhia kom lawv nyob ntsiag to. Nkauj ruam ruam? "Tseem" yog lus Southern uas hais tias " shut up .