qis tetraazoles, RCN4H, zoo li qis carboxylic acids, RCO2H, yog s soluble hauv dej thiab tsis tuaj yeem yooj yim crystalized los ntawm nws. tetrazoles qis dua yog crystallized zoo tshaj plaws los ntawm cov kuab tshuaj xws li ethyl acetate los yog toluene-pentane sib tov.
YPuas yog 1H tetrazole aromatic compound?
Structure and bonding
The 1H- and 2H- isomers yog tautomers, nrog rau qhov sib npaug ntawm 1H-tetrazole nyob rau theem khoom..
Puas yog tetrazole yooj yim?
Tsib Neeg Heterocycles
Nws yog a lub hauv paus tsis muaj zog heev nrog pKa ntawm -3.0 thiab protonation tshwm sim ntawm lub C4- txoj hauj lwm. Muaj tsis muaj zog nqus nyob rau hauv UV spectrum ntawm 5-hloov tetrazole hauv ethanol nyob ib ncig ntawm 200-220 nm. H NMR (D2O), δ (ppm): C5H, 9.5.
Vim li cas tetraazole yog cov kua qaub?
1.1.
Tetrazole qhia qhov kub ntawm qhov kub ntawm 155-157 ° C. … Qhov muaj N-H dawb ua rau cov kua qaub ntawm tetraazoles thiab tsim cov aliphatic thiab aromatic heterocyclic compounds. Heterocycles ntawm tetraazoles tuaj yeem tswj cov nqi tsis zoo los ntawm delocalization thiab qhia cov carboxylic acid pKa qhov tseem ceeb.
Cov tshuaj hauv qab no twg muaj tetrazole nucleus?
Qee cov tshuaj tetrazole xws li losartan, valsartan, irbesartanthiab candesartantwb tau siv rau kev kho mob ntshav siab hauv kev kho mob, ua kom pom lub peev xwm ntawm tetrazole derivatives li putative antihypertensive tshuaj [17].
