Methyl cyanide. Lus Qhia: Alkyl isocyanide ntawm kev txo qis nrog lithium aluminium hydride tsim cov amine theem nrab uas muaj methyl ua ib pawg alkyl.
Qhov twg yuav tsim cov amine thib ob ntawm cov tshuaj tiv thaiv nrog LiAlH4?
Ntawm qhov txo qis los yog nrog nascent hydrogen lossis nrog lithium aluminium hydride (LiAlH 4) alkyl isocyanide tawm los thib ob amine.
Cov tebchaw twg muab cov amine theem nrab ntawm kev txo qis?
Carbylamamines (los yog isocyanides) muab amine theem nrab ntawm kev txo qis.
Can LiAlH4 txo amines?
LiAlH4 yog ib qho muaj zog, tsis muaj kev xaiv txo tus neeg sawv cev rau polar ob daim ntawv cog lus, feem ntau yooj yim xav tias yog qhov chaw ntawm H-. Nws yuav txo aldehydes, ketones, esters, carboxylic acid chlorides, carboxylic acids thiab txawm carboxylate ntsev rau cawv. Amides thiab nitriles raug txo kom amines.
Puas LiAlH4 hnov mob nrog amines?
Nitriles tuaj yeem hloov pauv rau 1° amines los ntawm cov tshuaj tiv thaiv nrog LiAlH4. Thaum lub sij hawm no cov tshuaj tiv thaiv hydride nucleophile tawm tsam cov pa roj carbon electrophilic hauv nitrile los ua ib qho imine anion.