Glucocorticoids yog qhov tseem ceeb hauv zona fasciculata ntawm adrenal cortex, whereas mineralocorticoids yog synthesized nyob rau hauv lub zona glomerulosa. Cortisol (los yog hydrocortisone) yog qhov tseem ceeb tshaj plaws ntawm tib neeg glucocorticoid.
Glucocorticoid nyob qhov twg?
Glucocorticoids yog cov tshuaj steroid uas zais los ntawm cov qog adrenal. Lawv yog ib qho tseem ceeb rau kev saib xyuas ntawm basal thiab kev ntxhov siab txog homeostasis los ntawm kev ua raws li cov khoom kawg ntawm cov kev ntxhov siab teb hypothalamic-pituitary-adrenal (HPA) axis (1).
Cov tshuaj corticosteroids pom hauv lub cev nyob qhov twg?
Corticosteroids yog ib chav kawm ntawm cov tshuaj hormones steroid uas tau tsim nyob rau hauv adrenal cortex ntawm vertebrates, nrog rau cov khoom sib txuas ntawm cov tshuaj hormones.
Dab tsi ntawm lub cev tsim cov glucocorticoids?
Glucocorticoid, txhua yam tshuaj steroid uas tsim los ntawm qog adrenal thiab paub tshwj xeeb rau nws cov tshuaj tiv thaiv kab mob thiab tiv thaiv kab mob. Lub qog adrenal yog ib yam kabmob uas nyob rau saum lub raum. Nws muaj ib qho cortex sab nraud (adrenal cortex) thiab sab hauv medulla (adrenal medulla).
Dab tsi yog glucocorticoids hauv lub cev?
Glucocorticoids yog cov roj cholesterol-derived steroid hormones synthesized thiab secreted los ntawm lub qog adrenal. Lawv yog cov tshuaj tiv thaiv kab mob hauv txhua cov ntaub so ntswg, thiab tswj cov metabolism hauv cov leeg, rog, siab thiab pob txha. Glucocorticoids kuj cuam tshuam rau vascular tone, thiab hauv covlub hlwb cuam tshuam rau lub siab, tus cwj pwm thiab pw tsaug zog-wakefulness cycles.
