Nyob rau hauv pharmacokinetics thiab pharmacodynamics?

Cov txheej txheem:

Nyob rau hauv pharmacokinetics thiab pharmacodynamics?
Nyob rau hauv pharmacokinetics thiab pharmacodynamics?
Anonim

Hais lus yooj yim, pharmacokinetics yog 'lub cev ua rau tshuaj'. Pharmacodynamics piav qhia qhov kev siv ntawm cov tshuaj muaj feem xyuam rau nws cov concentration hauv cov kua hauv lub cev, feem ntau yog nyob ntawm qhov chaw ntawm kev siv tshuaj. Nws tuaj yeem yooj yim rau 'qhov tshuaj ua rau lub cev'.

Qhov txawv ntawm pharmacokinetics thiab pharmacodynamics yog dab tsi?

Pharmacokinetics yog kev kawm txog yam uas lub cev ua rau cov tshuaj, thiab Pharmacodynamics yog kev kawm txog yam tshuaj ua rau lub cev. … Yog li cov tshuaj pharmacokinetics hais txog txav ntawm txhua yam tshuaj nkag mus rau, dhau, thiab tawm ntawm lub cev.

Vim li cas nws tseem ceeb kom nkag siab txog cov tshuaj pharmacokinetics thiab pharmacodynamics?

Ob lub tshuaj pharmacokinetics (ADME) thiab cov tshuaj pharmacodynamics yog qhov tseem ceeb hauv txiav txim siab cov txiaj ntsig uas cov tshuaj tswj hwm yuav tsim. Extrinsic yam xws li raug ib puag ncig los yog cov tshuaj concomitant tuaj yeem cuam tshuam rau kev ua tau zoo ntawm cov tshuaj.

PK PD kev sib raug zoo yog dab tsi?

Abstract. Pharmacokinetic/pharmacodynamic (PK/PD)-modeling links dose-concentration kev sib raug zoo (PK) thiab concentration-effect kev sib raug zoo (PD), yog li pab txhawb kev piav qhia thiab kev kwv yees ntawm lub sijhawm ntawm cov tshuaj cuam tshuam tshwm sim los ntawm ib qho kev noj tshuaj.

4 kauj ruam ntawm cov tshuaj pharmacokinetics yog dab tsi?

Xav txog cov tshuaj pharmacokinetics raws li cov tshuaj taug kev hauv lub cev, thaum lub sijhawm nws dhau los ntawm plaub theem sib txawv:nqus, faib, metabolism, thiab tso tawm (ADME). Plaub kauj ruam yog: Absorption: Piav qhia seb cov tshuaj txav mus los ntawm qhov chaw tswj hwm mus rau qhov chaw ua haujlwm.

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