Nyob rau hauv biochemistry, ib qho metabolon yog ib ntus cov txheej txheem-kev ua haujlwm nyuaj tsim los ntawm cov enzymes txuas ntxiv ntawm txoj kev metabolic, tuav ua ke ob qho tib si los ntawm kev sib cuam tshuam tsis sib xws thiab los ntawm cov txheej txheem ntawm cov txheej txheem. cell, xws li integral membrane proteins thiab proteins ntawm cytoskeleton.
YYuav ua li cas yog metabolon hauv biochemistry?
Ib metabolon yog ib pawg ntawm cov enzymes hauv txoj kev biosyntheticuas teeb tsa kev sib txuas ntawm cov protein-protein sib cuam tshuam yog li tsim cov supramolecular complex nrog lub peev xwm los channel metabolites ntawm cov enzymes tivthaiv.
metabolon ua dab tsi?
Txoj kev ua neej. Metabolon decipers phav phav ntawm cov tshuaj tsis sib xws ntawm cov caj ces thiab tsis yog caj ces los qhia txog txoj hauv kev lom neeg. Peb ua kev sib txuas qhov twg lwm qhov 'omics tsis tuaj yeem, thiab muab qhov tseeb sawv cev ntawm phenotype.
Vim li cas cov metabolons tseem ceeb?
Metabolons yog protein complexes uas muaj tag nrho cov enzymes tsim nyog rau txoj kev metabolic tab sis kuj scaffolding proteins. Cov qauv zoo li no tso cai rau kev sib txuas ntawm cov metabolites nruab nrab ntawm ib qhov chaw nquag mus rau lwm qhov thiab muaj txiaj ntsig zoo rau labile lossis cov tshuaj lom neeg nruab nrab.
substrate channeling yog dab tsi thiab vim li cas nws tseem ceeb?
Qhov zoo ntawm lub cev zoo ntawm substrate channeling suav nrog tswj cov metabolic flux, tiv thaiv cov tshuaj tiv thaiv lossis tshuaj lomintermediates, nce catalytic efficiency, thiab txo diffusion ntawm intermediates deb ntawm catalytic sites.