Vim li cas muscarinic receptor antagonist?

Cov txheej txheem:

Vim li cas muscarinic receptor antagonist?
Vim li cas muscarinic receptor antagonist?
Anonim

Muscarinic receptor antagonists (MRAs) ua haujlwm los ntawm kev sib tw thaiv cov lus teb cholinergic uas tshwm sim los ntawm acetylcholine (ACh) khi muscarinic receptors ntawm exocrine glandular cells, plawv cov leeg nqaij, thiab cov leeg nqaij..

siv cov muscarinic antagonist yog dab tsi?

Tshuaj nrog muscarinic antagonist kev ua ub no tau siv dav hauv cov tshuaj, hauv kev kho mob ntawm lub plawv dhia qis, zais zis ntau dhau, teeb meem ua pa xws li mob hawb pob thiab COPD, thiab teeb meem neurological xws li Parkinson's disease thiab Alzheimer's disease.

Cov txiaj ntsig kho li cas thaum cov tshuaj antagonist khi rau muscarinic receptor?

Muscarinic antagonists inhibit the contractions of the gastrointestinal tract induced by Ach and other muscarinic agonists mediated via M3 receptors. Lawv, txawm li cas los xij, feem ntau tsis tshua muaj txiaj ntsig tiv thaiv qhov nce hauv kev cog lus thiab kev txav mus los vim qhov kev xav ntawm cov hlab ntsha parasympathetic.

Vim li cas cov tshuaj muscarinic antagonists tsis siv rau mob hawb pob?

Nyob rau hauv mob hawb pob, muscarinic antagonists tau xav tias tsis zoo li bronchodilators dua li β2-agonists, raws li cholinergic feem ntawm bronchoconstriction tau ntseeg. kom me me piv rau qhov ncaj qha constrictor los ntawm inflammatory mediators los yog leukotrienes [4].

Qhov kev txiav txim ntawm muscarinic receptor yog dab tsi?

[2] Muscarinic receptors koom nrog peristalsis, micturition, bronchoconstriction, thiab ob peb lwm yam tshuaj tiv thaiv parasympathetic. [3][4][5] Muscarinic receptors yog ib hom ligand-gated G-protein coupled receptor, ua haujlwm raws li kev tswj hwm G-proteins (Gs) lossis inhibitory tswj G-proteins (Gi).

Pom zoo:

Nthuav cov khoom
Yuav ua li cas thaum lub tuam txhab rov txhim kho?
Nyeem ntxiv

Yuav ua li cas thaum lub tuam txhab rov txhim kho?

Kev rov txhim kho yog qhov tseem ceeb thiab cuam tshuam kev kho dua tshiab ntawm kev lag luam teeb meem npaj los kho nws kom muaj txiaj ntsig. Tej zaum nws yuav suav nrog kaw lossis muag kev faib tawm, hloov kev tswj hwm, txiav nyiaj txiag, thiab tso cov neeg ua haujlwm.

Thaum ci qhov cub qhov twg?
Nyeem ntxiv

Thaum ci qhov cub qhov twg?

Thaum siv qhov cub nrog ob qhov kiv cua-tsim thiab cov chaw ua haujlwm, nws yog qhov zoo tshaj plaws los siv pajthaum koj ci ntev thiab qeeb (xws li ncuav qab zib) thiab kiv cua yuam rau ua noj ceev ceev ntawm qhov kub thiab txias. Yog tias siv lub qhov cub kom kiv cua, raws li txoj cai dav dav, txo qhov kub ntawm 20 ° C kom ua raws li cov lus pom zoo.

Puas yog cov neeg ua haujlwm tawm tswv yim?
Nyeem ntxiv

Puas yog cov neeg ua haujlwm tawm tswv yim?

Cov neeg ua haujlwm tawm tswv yim txhais tau yooj yim heev: nws yog kev nce qib ntawm koj lub tuam txhab los ntawm cov neeg ua haujlwm rau nws. … Kev tawm tswv yim rau cov neeg ua hauj lwm raws li kev lag luam tawm tswv yim yog ib txoj haujlwm zoo, muaj txiaj ntsig zoo los txhawb cov neeg ua haujlwm kom qhia cov khoom muaj txiaj ntsig thiab cov lus hauv ib txoj hauv kev.