Puas yog nortriptyline thiab amitriptyline tib yam?

Cov txheej txheem:

Puas yog nortriptyline thiab amitriptyline tib yam?
Puas yog nortriptyline thiab amitriptyline tib yam?
Anonim

AMITRIPTYLINE thiab NORTRIPTYLINE yog dab tsi? Amitriptyline thiab Nortriptyline yog los ntawm ib pawg tshuaj hu ua tricyclic antidepressants. Lub cev hloov pauv amitriptyline rau nortriptyline, yog li cov teebmeem ntawm ob yam tshuaj zoo ib yam.

Qhov txawv ntawm nortriptyline thiab amitriptyline yog dab tsi?

Amitriptyline yog cov tshuaj ntawm kev xaiv hauv kev kho mob kev nyuaj siab thaum cov kev mob tshwm sim ntawm kev mob me me yog qhov xav tau. Nortriptyline yog siv thaum nws cov kev mob tshwm sim tshwm sim tau suav tias yog qhov zoo ntawm kev kho mob.

Puas yog nortriptyline muaj zog dua li amitriptyline?

Hauv kev tshawb fawb tsiaj uas siv cov lus teb rau qhov mob stimulus, amitriptyline muaj zog ntau duanortriptyline, imipramine, thiab desipramine. Amitriptyline tau txiav txim siab tias muaj kwv yees li 70 npaug ntau dua li cov tshuaj aspirin ua tshuaj tua kab mob.

Qhov twg zoo dua rau qhov mob nortriptyline lossis amitriptyline?

Thaum muab tshuaj TCAs [tricyclic antidepressants], cov amines theem nrab (nortriptyline, desipramine) feem ntau ua tau zoo dua nyob rau hauv cov nqe lus ntawm sedation, postural hypotension, thiab anticholinergic teebmeem thaum piv nrog tertiary amines (amitriptyline thiab imipramine) nrog rau kev sib piv cov tshuaj tua kab mob.

Puas yog nortriptyline sedating dua amitriptyline?

Nortriptyline yog ib qho tricyclic anti-depressant thiab ib qho nquag metabolite ntawm amitriptyline. Nws blocks lub pre-synaptic re-uptake ntawm noradrenaline thiab inhibits cov kev ua ntawm serotonin, histamine thiab acetylcholine. Nws muaj cov nyhuv sedative uas pab txhim kho kev pw tsaug zog tab sis feem ntau tsawg sedating dua amitriptyline.

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