Orexin cuam tshuam li cas rau kev tshaib kev nqhis?

Cov txheej txheem:

Orexin cuam tshuam li cas rau kev tshaib kev nqhis?
Orexin cuam tshuam li cas rau kev tshaib kev nqhis?
Anonim

Tab sis orexin kuj tseem ceeb heev uas yog tus neeg nruab nrab ntawm kev qab los noj mov. Muab orexin yuav ua rau muaj kev xav tau zaub mov, thiab muab cov tshuaj hormones zoo li leptin (lub teeb liab ntawm kev ua kom puv), inhibits orexin. Thiab qhov no txhais tau hais tias orexin tuaj yeem yog lub hom phiaj tshiab rau cov teeb meem cuam tshuam nrog kev qab los noj mov, tshwj xeeb yog tej yam xws li noj binge.

Puas orexin nce lossis txo kev tshaib kev nqhis?

Cov pov thawj tseem ceeb qhia tau hais tias orexin-A nce zaub mov ntau ntxivlos ntawm kev ncua qhov pib ntawm tus cwj pwm zoo li qub satiety ib ntus. Hauv qhov sib piv, ib qho kev xaiv orexin-1 receptor antagonist (SB-334867) inhibits kev noj zaub mov thiab nce qhov pib ntawm ib txwm satiety sequence.

Dab tsi yog ob qhov cuam tshuam ntawm orexin tso tawm?

Kev tswj hwm nruab nrab ntawm orexin-A muaj zog txhawb kev tsaug zog, nce lub cev kub thiab txav chaw, thiab txhawb nqa kev siv zog ntxiv.

orexin cuam tshuam li cas?

Orexin neurons txhawb kev tsaug zog los ntawm monoaminergic nuclei uas yog tsim los. … Peripheral metabolic signals cuam tshuam orexin neuronal kev ua haujlwm los tswj kev xav thiab lub zog homeostasis. Kev txhawb nqa ntawm neuropeptide Y neurons los ntawm orexin nce kev noj zaub mov.

Yog ghrelin lossis orexin?

Ghrelin tseem muaj peev xwm los txhawb Fos qhia hauv orexin-ua cov neurons tom qab pretreatment nrog anti-NPY IgG, qhia tias ghrelin activates orexin-tsim neurons.raws li kev ywj pheej ntawm NPY.

Pom zoo: