Hexokinase IV muaj nyob hauv lub siab, pancreas, hypothalamus, txoj hnyuv me, thiab tej zaum qee lwm cov hlwb neuroendocrine, thiab ua lub luag haujlwm tseem ceeb hauv kev tswj cov carbohydrate metabolism.
hexokinase nyob qhov twg hauv lub cev?
Hexokinase IV qhia txog kev sib koom tes zoo nrog cov piam thaj thiab tsis cuam tshuam los ntawm cov piam thaj-6-phosphate, tsis zoo li hexokinases I, II thiab III. Nws muaj nyob hauv lub siab, txiav txiav, hypothalamus thiab txoj hnyuv. Nws kuj tseem tuaj yeem muaj nyob hauv lwm cov hlwb neuroendocrine.
YPuas hexokinase pom nyob rau hauv tag nrho cov ntaub so ntswg?
-Hexokinase I/A tau pom nyob rau hauv tag nrho cov ntaub so ntswg mammalian, thiab suav hais tias yog "lub tsev tu enzyme," tsis cuam tshuam los ntawm feem ntau lub cev, hormonal, thiab metabolic hloov.
YPuas muaj glucokinase nyob rau hauv tag nrho cov ntaub so ntswg?
Glucokinase tau tshawb pom hauv cov hlwb tshwj xeeb hauv plaub hom tsiaj cov ntaub so ntswg: daim siab, pancreas, hnyuv me, thiab hlwb. Txhua lub luag haujlwm tseem ceeb hauv kev teb rau qhov nce lossis poob qib ntawm cov ntshav qabzib. Cov hlwb tseem ceeb ntawm daim siab yog cov hepatocytes, thiab GK pom tshwj xeeb hauv cov hlwb no.
YPuas yog hexokinase hauv cov leeg nqaij?
Hexokinase isoforms nyob rau hauv tib neeg skeletal nqaij . Hexokinase isozymes I thiab II tau qhia hauv cov leeg pob txha (3). Cov leeg nqaij pob txha muaj feem ntau hom II enzyme (1, 5), thaum tib neeg cov leeg muaj kwv yees li sib npaugntau hom II thiab hom I isoforms (19, 21, 40).
