Thiazide diuretics yog cov tshuaj uas ua rau ob qho tib si natriuresis (tshem tawm sodium hauv cov zis) thiab diuresis. Thiazide diuretics ua haujlwm los ntawm kev thaiv cov sodium thiab chloride (Na / Cl) channels nyob rau hauv lub distal convoluted tubule ntawm nephron thiab inhibit reabsorption ntawm sodium thiab dej.
Yuav ua li cas thiazide diuretics ua haujlwm hauv nephron?
Thiazide diuretics yog FDA-pom zoo cov tshuaj uas inhibit reabsorption ntawm 3% mus rau 5% ntawm luminal sodium nyob rau hauv lub distal convoluted tubule ntawm nephron. Los ntawm kev ua li ntawd, thiazide diuretics txhawb nqa natriuresis thiab diuresis.
Yuav ua li cas thiazide diuretics ua nyob rau hauv lub raum?
Thiazide diuretics yog dab tsi? Thiazide diuretics yog ib hom tshuaj diuretic (ib yam tshuaj uas ua rau cov zis tso zis ntau ntxiv). Lawv ua ncaj qha rau ntawm lub raum thiab txhawb cov diuresis (cov zis ntws) los ntawm inhibiting cov sodium / chloride cotransporter nyob rau hauv lub distal convoluted tubule ntawm nephron (lub luag haujlwm ntawm lub raum).
Cov tshuaj thiazide diuretic ua haujlwm nyob qhov twg?
Mechanisms of Action
Ib yam khoom tseem ceeb ntawm thiazide diuretics yog lawv qhov kev txiav txim ntawm lub luminal membrane, uas txhais tau tias lawv yuav tsum muaj nyob rau hauv cov kua dej kom muaj cov cuam tshuam rau Na/Cl co-transporter.
5 hom tshuaj diuretics yog dab tsi?
hom tshuaj diuretics
- chlorthalidone.
- Yhydrochlorothiazide (Microzide)
- metolazone.
- Yindapamide.
15 cov lus nug ntsig txog pom
Cov kev mob tshwm sim ntawm lub voj diuretics yog dab tsi?
Kev mob tshwm sim ntau thiab sib koom ntawm lub voj diuretics suav nrog kiv taub hau, mob taub hau, mob plab hnyuv, hypernatremia, hypokalemia thiab lub cev qhuav dej.
Qhov twg thiazide diuretic yog qhov zoo tshaj?
Hydrochlorothiazide (HCTZ) thiab chlorthalidone yog ob qho tib si thiazide diuretics pom zoo ua thawj cov kev xaiv rau kev kho ntshav siab vim tias lawv cov txiaj ntsig ntawm lub plawv noj qab haus huv thiab tag nrho cov neeg tuag.
Dab tsi yog qhov tshwm sim tshwm sim ntawm thiazide diuretics?
Cov kev mob tshwm sim suav nrog tso zis ntau ntxiv thiab poob sodium. Diuretics tseem tuaj yeem cuam tshuam cov ntshav cov ntshav potassium. Yog tias koj noj thiazide diuretic, koj cov poov tshuaj tuaj yeem poob qis dhau (hypokalemia), uas tuaj yeem ua rau muaj teeb meem rau lub neej nrog koj lub plawv dhia.
Lub luag haujlwm ntawm kev ua haujlwm twg piav qhia yuav ua li cas hydrochlorothiazide nce zis tso zis?
Mechanism of Action
Thiazides nce zis by inhibiting the NaCl cotransporter on the luminal membrane of the earliest part of the distal convoluted tubule, feem ntau hu ua cortical diluting ntu (Fig. 9-5).
Dab tsi yog diuretic zoo tshaj plaws rau ntshav siab?
Lub ntsiab diuretic siv niaj hnub no yog hydrochlorothiazide, lossis HCTZ, uas muaj kev phiv tsawg dua li chlorthalidone, diuretic siv hauv txoj kev tshawb no. HCTZ feem ntau ua ke nrog lwm cov tshuaj diuretics rau hauv ib ntsiav tshuaj.
Yuav ua li cas diuretics cuam tshuam rau lub raum?
tshuaj diuretic nce zis tso zis los ntawmlub raum (piv txwv li, txhawb diuresis). Qhov no ua tiav los ntawm kev hloov pauv lub raum ua haujlwm li cas sodium. Yog hais tias lub raum excretes sodium ntau, ces dej excretion kuj nce.
Yuav tshuaj twg yog diuretic muaj txiaj ntsig zoo?
Loop diuretics yog cov tshuaj diuretics uas muaj zog tshaj plaws vim lawv ua rau kom tshem tawm sodium thiab chloride los ntawm feem ntau tiv thaiv reabsorption ntawm sodium thiab chloride. Qhov kev ua tau zoo ntawm lub voj diuretics yog vim qhov chaw tshwj xeeb ntawm kev ua cuam tshuam nrog lub voj ntawm Henle (ib feem ntawm lub raum tubule) hauv ob lub raum.
Yuav ua li cas diuretics ua haujlwm hauv nephron?
Diuretics ua feem ntau los ntawm kev thaiv cov reabsorption ntawm sodium ntawm plaub qhov chaw loj hauv nephron. Cov kws kho mob muaj txiaj ntsig zoo uas thaiv cov sodium reabsorption zoo hauv proximal tubuletsis muaj.
Yuav ua li cas diuretics ua rau nephron?
Lawv ua los ntawm txo qis sodium reabsorption ntawm ntau qhov chaw hauv nephron, yog li ua rau tso zis sodium thiab dej poob. Ib chav kawm thib ob ntawm cov tshuaj diuretics, qee zaum hu ua aquaretics, es tsis txhob cuam tshuam cov dej reabsorption los ntawm kev thaiv cov vasopressin receptors raws cov tubule txuas thiab sib sau cov duct.
thiazide ua dab tsi rau tso zis?
Renal System
Thiazides nce zis tso zis los ntawm inhibiting NaCl cotransporter ntawm lub luminal membrane ntawm qhov ntxov tshaj plawsntawm qhov distal convoluted tubule, feem ntau hu ua cortical diluting ntu (Fig.
Kuv yuav tsum haus dej ntxiv thaum noj HCTZ?
Ceev faj kom tsis txhob kub dhau los yog lub cev qhuav dejthaum huab cua kub thaum noj hydrochlorothiazide. Tham nrog koj tus kws kho mob txog seb koj yuav tsum haus dej npaum li cas; Qee zaum kev haus dej ntau dhau yog qhov teeb meem zoo li tsis haus dej txaus.
Leej twg yuav tsum tsis txhob noj cov tshuaj diuretics?
Nug koj tus kws kho mob yog tias koj yuav tsum zam lossis ceev faj siv cov tshuaj diuretics yog tias koj:
- Muaj daim siab lossis raum mob hnyav.
- Ntau lub cev qhuav dej.
- Hlub plawv dhia tsis tu ncua.
- Puas yog nyob rau peb lub hlis twg ntawm cev xeeb tub thiab/los yog muaj ntshav siab thaum koj cev xeeb tub.
- Yog hnub nyoog 65 xyoos lossis tshaj saud.
- muaj gout.
Dab tsi yog qhov muaj zog diuretic?
Loop diuretics (furosemide thiab bumetanide) yog cov muaj zog tshaj plaws ntawm cov tshuaj diuretics thiab tau siv dav hauv kev kho mob ntsws thiab kab mob edema.
Puas 50 mg ntawm hydrochlorothiazide ntau dhau lawm?
Cov Neeg Laus-Thaum xub thawj, 12.5 milligrams (mg) lossis ib ntsiav tshuaj ib hnub ib zaug. Koj tus kws kho mob yuav xav kom koj noj qhov no ib leeg lossis ua ke nrog lwm cov tshuaj ntshav siab. Koj tus kws kho mob tuaj yeem nce koj cov koob tshuaj raws li qhov xav tau. Txawm li cas los xij, koob tshuaj feem ntau tsis ntau tshaj 50 mg ib hnub.
Vim li cas thiazide zoo li diuretics nyiam?
Rau cov neeg mob ntshav qab zib mellitus, American Diabetes Association muab kev nyiam rau thiazide-zoo li diuretics (chlorthalidone thiab indapamide) vim tias lawv yog cov tshuaj diuretics ntev dua uas muaj pov thawj cuam tshuam rau kev txo cov hlab plawv [45].
Thaum twg yuav tsum tsis txhob siv thiazide diuretic?
Tus neeg muajntshav qab zib tuaj yeem muaj ntshav qab zib ntau ntxiv thaum noj thiazide diuretics. Nws tsis pom zoo kom siv thiazide diuretics nrog dofetilide (Tikosyn), cov tshuaj siv los kho lub plawv dhia tsis zoo, vim qhov no tuaj yeem ua rau cov ntshav nce qib ntawm dofetilide (Tikosyn) thiab ua rau lub plawv dhia tsis zoo.
Yuav ua li cas kom diuretic sai sai?
Koj feem ntau noj cov tshuaj maj, ua kom ntev ntev los ntawm qhov ncauj ib hnub thaum sawv ntxov. Cov teebmeem ntawm bendroflumethiazide (bendrofluazide) pib hauv 1-2 teev ntawm kev nojthiab tuaj yeem ua rau koj tso zis ntau dua rau thawj 14 hnub thaum noj.
Loop diuretics ua haujlwm hauv lub cev li cas?
Loop diuretics ua haujlwm li cas? Lawv ua hauj lwm ua rau lub raum hla dej ntau dua. Lawv ua qhov no los ntawm kev cuam tshuam nrog kev thauj cov ntsev thiab dej hla qee cov cell hauv ob lub raum. (Cov hlwb no nyob hauv cov qauv hu ua lub voj ntawm Henle - yog li lub npe voj diuretic.
Pob diuretics nce bilirubin?
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