YPyrimidine synthesis tshwm sim hauv
cytoplasm. Pyrimidine yog synthesized li lub nplhaib pub dawb thiab tom qab ntawd ib qho ribose-5-phosphate ntxiv rau cov txiaj ntsig ncaj qha nucleotides, whereas, hauv purine synthesis, lub nplhaib yog tsim los ntawm kev txuas atoms ntawm ribose-5-phosphate.
Yuav ua li cas kauj ruam ntawm pyrimidine biosynthesis tshwm sim hauv mitochondria?
De novo biosynthesis ntawm pyrimidine Nov yog cov kauj ruam tswj hwm hauv pyrimidine biosynthesis hauv cov kab mob. Lub nplhaib tsim thiab Lub cev qhuav dej. Dihydroorotate ces nkag mus rau mitochondria qhov twg nws yog oxidized los ntawm kev tshem tawm ntawm hydrogens. Qhov no tsuas yog mitochondrial kauj ruam hauv nucleotide rings biosynthesis.
Nucleotide synthesis tshwm sim nyob qhov twg hauv cell?
De novo purine nucleotide synthesis tshwm sim nyob rau hauv cytosol ntawm lub siab qhov twg tag nrho cov enzymes tsim nyog muaj tam sim no raws li macro-molecular aggregate.
thawj pyrimidine synthesized yog dab tsi?
thawj kauj ruam hauv de novo pyrimidine biosynthesis yog synthesis ntawm carbamoyl phosphate los ntawm bicarbonate thiab ammonianyob rau hauv ntau txoj kev, yuav tsum tau cleavage ntawm ob molecules ntawm ATP. Cov tshuaj tiv thaiv no yog catalyzed los ntawm carbamoyl phosphate synthetase (CPS) (Tshooj 23.4. 1).
Purine synthesis tshwm sim nyob rau hauv lub cell nyob qhov twg?
Purine biosynthesis tshwm sim hauv cytosol ntawm txhua lub hlwb. Lub nplhaib purine yog tsim los ntawm 11 enzyme catalysedcov kauj ruam. Txhua enzyme yog oligomeric, uas txhais tau hais tias nws muaj ob peb monomers. Cov khoom nruab nrab uas tsim tawm thaum lub sijhawm cov tshuaj tiv thaiv tsis tso tawm.
