2024 Tus sau: Elizabeth Oswald | [email protected]. Kawg hloov kho: 2024-01-13 00:07
Phosphodiesterases (PDEs) yog cov enzymes uastswj cov qib hauv cov cell ntawm cyclic adenosine monophosphate thiab cyclic guanosine monophosphate, thiab, yog li, nthuav tawm lub luag haujlwm tseem ceeb hauv ntau lub zog ntawm tes.
phosphodiesterase ua dab tsi hauv lub siab?
Hauv cov neeg mob plawv tsis ua hauj lwm, inhibitors ntawm enzymes hauv PDE3 tsev neeg ntawm cyclic nucleotide phosphodiesterases yog siv los nce intracellular cAMP cov ntsiab lus hauv cov leeg nqaij, nrog inotropic ua.
Phosphodiesterase inhibitors ua li cas?
Mechanism of Action
[16][17][18] Phosphodiesterase inhibitors exert lawv cov teebmeem ntawm lawv cov phiaj xwm phosphodiesterase enzymes(PDE-3, PDE-4, PDE-5), tiv thaiv cGMP lossis cAMP degradation, ntxiv rau lawv cov qib hauv cov leeg nqaij, ua rau kom so thiab vasodilatory nyhuv hauv cov hlwb.
PDE inhibitors ua dab tsi?
Phosphodiesterase 5 (PDE 5) inhibitors yog ib hom hom phiaj kho mob siv los kho cov neeg mob pulmonary hypertension (PH). Cov phiaj xwm kho mob qeeb qeeb ntawm PH thiab tuaj yeem thim rov qab qee qhov kev puas tsuaj rau lub plawv thiab ntsws.
phosphodiesterase 5 yog dab tsi?
PDE5 yog ib qho tseem ceeb enzyme koom nrog kev tswj hwm ntawm cGMP-kev taw qhia tshwj xeeb hauv cov txheej txheem physiological xws li cov nqaij leeg du thiab so. Vim li no, inhibition ntawm lubenzyme tuaj yeem hloov cov kab mob pathophysiological cuam tshuam nrog kev txo qis cGMP hauv cov ntaub so ntswg.
Pom zoo:
Kab lus nrog lo lus dab tsi yog dab tsi?
Lore kab lus piv txwv. -Npauj npaim yog ib yam tsiaj zoo ntawm cov dab neeg thaum ub thiab kev lig kev cai. Nws obtrudes nws tus kheej hauv kev kos duab zoo nkauj, kev coj cwj pwm, kev cai lij choj, kev ntseeg thiab kev ntseeg. Yuav ua li cas piv txwv ntawm lore?
Puas yog cov dab dab dab dab dab dab dab dab dab dab dab dab?
Myth: Ib tug dab tshos tsis yog neeg ncaj ncees yog tiasnws haum yog. Fact: Tu siab, qhov no yog ib lo lus tsis tseeb uas tau raug perpetuated los ntawm aversive trainers. Txawm hais tias haum rau lub caj dab kom zoo khawb rau hauv cov tawv nqaij rhiab nyob ib ncig ntawm lub caj dab, uas ua rau muaj kev puas tsuaj loj rau cov thyroid, esophagus, thiab trachea.
Tus mob twg kho tau siv phosphodiesterase-4 inhibitor?
Tseeb, xaiv PDE4 inhibitors tau tsim muaj txiaj ntsig zoo raws li kev kho mob rau ntau yam kab mob autoimmune suav nrog ankylosing spondylitis, Alzheimer's disease, psoriasis, psoriatic mob caj dab, sarcoidosis, kab mob lupus erythematosus, inflammatory kab mob hauv plab, atopic dermatitis, mob caj dab rheumatoid, … phosphodiesterase 4 inhibitor ua dab tsi?
Dab tsi yog tus bestiary hauv dab dab dab?
Wiki Targeted (Kev Ua Si) Beasts yog cov lus hu uas muab Metropolitan Era monsters txhawb nqa rau stats nrog rau cov txiaj ntsig hauv kev sib ntaus sib tua. Tus Bestiary tuaj yeem kho tau ntawm qib 18, qhov twg cov neeg ua si tuaj yeem qhib thiab nce qib Beasts los txhim kho lawv lub zog thiab cov teebmeem.
Puas yog cov dab dab dab dab dab dab tau them?
OHL cov neeg ua si tsis tau nyiaj hli, vim lawv tsis raug lees paub tias yog cov neeg ua haujlwm raws li Txoj Cai Kev Ua Haujlwm. Txawm li cas los xij, lawv suav nrog cov txiaj ntsig xws li nyiaj rov qab txhua xyoo, tag nrho cov nqi kawm ntawv them, thiab daim pib pub dawb.
